Autophagy is a mechanism of our body that helps us to be healthy. Although the human body is healthy, cells experience damage during various metabolic processes. As we age, our body is under constant stress with more and more damage caused by the action free radicals . Our cells become more exposed to damage and the action of toxins.
In addition, as the organism ages, metabolic processes slow down, the endocrine system and the structure of hormones change. In that case, the organism is also exposed to greater stress and certain changes occur.
Then he performs on stage autophagy . This process in the body helps our body get rid of damaged cells. Targets include active cells that have no role in the body. Cells that represent excess and also malignant cells .
It is very important for the body to get rid of damaged, unusable and malignant cells because they can indicate inflammatory reactions or some very serious diseases.
The word autophagy was coined several decades ago and consists of two Greek words. The first is “auto” (meaning self) and the second is “phagy” (meaning to eat).
In recent studies, researchers have been able to understand how this complex part of our immune system can affect our longevity, improve our immune system, our heart and complete metabolism .
What is autophagy and is it good or bad for you?
The definition of autophagy is the consumption of the tissues of one’s own organism in the form of a metabolic process that occurs due to starvation or due to various diseases. Researchers believe that autophagy is a survival mechanism. In that way, the organism reacts to stress and tries to protect itself.
Is it autophagy good or bad for your health? She is definitely good! As I mentioned, you can consider autophagy as a form of self-devouring. This may sound scary, but this is a normal process of the body during which cells renew themselves. Autophagy is so helpful that it is the key to preventing diseases such as cancer, neuronal degeneration, diabetes, liver disease and autoimmune disorders , as well as for infections.
Autophagy there are many benefits that help with aging. Autophagy uses waste produced in cells to produce building material for the repair and regeneration of other cells.
Thanks to the latest studies, we know that autophagy cleanses the body and protects it from the negative effects of stress. Scientists are still researching the way and processes of autophagy and how it actually affects the organism.
There are several processes involved in autophagy. Lysosomes are parts of cells that can destroy large damaged structures, such as mitochondria. These cell parts can also help in transporting these damaged cell parts in order to generate energy. The sum of the sumarum, of the complete process, is that in fact the damaged material must first be transported by the lysosome, then reconstructed, and then used for a new purpose.
Researchers have hinted at the most important good properties of autophagy for our body:
Providing building material and energy for cells.
Recycling of damaged proteins and waste
Regulation of the drive functions of cells, mitochondria, which serve to produce energy and can be damaged due to oxidative stress and anaerobic state of the cell due to physical exertion, disease or the influence of certain hormones on cells and their receptors
Protects nerve system and stimulates the development of new brain cells. Autophagy improves cognitive functions, brain structure and neuroplasticity.
Autophagy promotes the growth and development of heart muscle cells. It also protects the heart from heart disease.
Improves and modifies the immune system by eliminating intercellular pathogens. It also reduces toxicity in the body in this way and thus protects DNA.
Prevents damage to healthy tissues. It destroys cancer , fights neurodegenerative diseases.
There are several different types of autophagy. Science knows macroautophagy, microautophagy and protective autophagy. Macroautophagy is a catabolic process by which vesicles are formed that swallow cellular macromolecules and organelles. This is the most commonly used form.
The human species is not the only one to have the benefits of autophagy. Autophagy It also occurs in plants, worms, flies and other mammals. A lot of research with autophagy has been conducted on rats. 32 genes associated with autophagy have been isolated. Research has continued and their course is very important because in this way I can discover many new details related to this metabolic activity of the organism.
Scientists believe that autophagy is a selectin when removing certain organelles, ribosomes and protein aggregates from the human body. There is currently no information that autophagy or apoptosis (programmed cell death) regulate some other processes in the body. Some studies confirm the fact that autophagy is a mechanism of apoptosis.
One of the reasons why researchers are interested in the connection between autophagy and apoptosis is the belief that autophagy can treat cancer and neurodegenerative diseases such as Alzheimer’s disease. Autophagy can act as a therapeutic process in the body, by which we purposefully remove unwanted cells and keep them healthy.
In the future, we can use the process of autophagy to protect cells and their renewal and destruction of cells that cause diseases and inflammation in the body.
How to enhance autophagy?
Autophagy is active in all cells, but it intensifies when food intake decreases, more precisely, we starve the organism. This goal can be achieved through exercise, physical activity and reducing calorie intake. Both methods are associated with weight control, longer life expectancy and the prevention of many age-related diseases.
When we use diet and adjust life habits to boost autophagy activity, the best trigger is fasting. The best dietary strategy is so-called intermittent fasting. Pos has a very simple concept and that is to stop eating for a certain period of time (you can still drink water during fasting or liquids like coffee and tea).
If you are unfamiliar with intermittent fasting, this type of cyclic diet includes time-restricted periods of diet. There are many different forms of intermittent fasting that enhance autophagy such as Alternative Daily Fasting in which you limit your daily food intake between 4 and 8 days.
Studies have shown that fasting between 24 and 48 hours has the strongest effect, but this type of fasting is not feasible for all people. Try at least between 12 and 36 o’clock if the above figure doesn’t work for you.
The easiest way to achieve your desired goal is to eat 1 or 2 meals a day instead of much smaller meals. If you finish dinner at 6 or 7 o’clock try to starve until at least 7 o’clock in the morning the next day or even better until 11 or 12 o’clock.
You can choose 2-3 days of fasting, it can even be longer when you become experienced enough and get your body used to fasting.
Ketogenic or KETO diet is a diet with a large amount of healthy fats, and a small amount of carbohydrates and this diet works very similar to fasting. The keto diet works by getting 75% of your daily calories or more from healthy fats. and only 5 to 10% of calories from carbohydrates. This affects your body so that there are some key changes in it. Metabolic pathways are beginning to use fats as fuel instead of glucose from carbohydrates.
What types of food are most important if you are planning to start a Catogenic diet? Use coconut oil for food, olive oil, eggs, peanut butter, meat from animals fed exclusively on grass, fermented cheese, avocado, smoothies and pits. Fruit is also included because of the necessary fiber for the digestive tract and because of the vitamins and anti-oxidant properties it possesses.
In response to reduced carbohydrate intake, ketones will begin to be produced which have many protective effects on your body. Studies have shown that ketosis can also activate aphagia, which has a neuroprotective function. In studies in rats, the keto diet activated the metabolic processes of autophagy activators, and on that occasion, brain injuries in injured rats were reduced.
Another good stress that can activate autophagy is exercise. Recent research shows that exercise can activate autophagy in various organs, including the metabolic regulation of muscles, liver and pancreas.
There are many good sides to exercise, it is a form of stress because it destroys the tissue, causing its repairs and growth in a stronger form. It is not yet clear how much exercise enhances autophagy, but researchers believe it is best for boosting autophagy.
Exercising for 30 minutes enhances autophagy in the skeletal and muscular system. Can we exercise during fasting? Most people can. You may also notice that you get a big influx of energy when you stop fasting, which can motivate you even more to exercise.
Safety measures during fasting
We learned a lot of things about autophagy through this text. By increasing autophagy through fasting and regular exercise, we achieve excellent results.
But, if you are taking certain medications to control your health condition, it is best to consult a doctor before you start fasting. People who suffer from hypoglycemia or diabetes and women who are pregnant, breastfeeding, should not fast. Anyone who has diseases such as cancer should consult their doctor before fasting.
Seven important questions and answers about autophagy
Autophagy is a body recycling program and is essential for every cell. when the autophagy procedure is carried out efficiently, you will feel more energetic, agony, clearer, the skin will begin to take on a youthful glow. Autophagy is an amazing natural cell rejuvenator and is very effective. Autophagy stops accelerated aging and at the same time helps you feel and look better.
Although coffee enhances autophagy, there is also a simple and delicious way to get up without a caffeine rush. combine one bag of green tea with one bag of citrus bergamot tea as well as one tablespoon of raw coconut oil with a cinnamon stick. This drink warms the body, it can be drunk at any time of the day. The effects of this drink are to burn fat, improve brain function, strengthen immunity and make the skin glow.
Citrus bergamot is one of the best and healthiest autophagy activators in the world. It protects the heart and green tea polyphenols such as EGCG stimulate autophagy and a process called thermogenesis (calorie burning rate). Cinnamon is neuroprotective and can protect cells from damage and cancer. Coconut oil increases the level of ketones, which have been found to have anti-autophagy so that you feel fulfilled at the same time.
Autophagy is activated when cells go through a certain amount of stress. It has been proven that limiting calorie intake induces a process that helps cells become stronger and longer-lasting by conserving energy. One of the easiest ways to start autophagy is fasting. Practicing fasting does not mean that you have to starve. To trigger autophagy is to be without food for 16 hours. This can be achieved if you eat an early dinner and skip breakfast or have breakfast later than usual. If you apply it for only three days in a row, the body activates autophagy, giving the cells a chance to rest, cleanse any waste and toxins that have accumulated in the body.
OMI’s patented cell rejuvenation complex consists of premium ingredients that have been clinically proven to activate autophagy. The ingredients are citrus bergamot, ceramide, trichlose and caffeine. Although each of these ingredients individually will do wonders for your complexion, including the renewal of the skin barrier, increasing moisture and reducing inflammatory processes. Together, these ingredients are much more powerful, improving the nutrition of the skin, which it needs for youth and radiance.
Studies show that in just 30 minutes of exercise, autophagy is caused in the heart and bone muscle cells. One of the best ways to achieve this and at the same time to take advantage of all the other benefits of exercise such as HIIT-interval training of high intensity. This training includes exercising at short intervals and resting. By repeatedly pressing on your anaerobic threshold, you amplify the effects of autophagy and improve the health of mitochondria in cells. This way of exercising can be applied during any activity that you normally perform, such as swimming, running or brisk walking.
Resveratrol is a super powerful polyphenol found in the skin of red grapes, peanuts and berries. Many studies have shown that resveratrol works wonders for the human body. It prevents the decline of cognitive functions by increasing blood flow and reducing inflammation in the brain. resveratrol also activates sirtuins that increase metabolism, improve the health of the cardiovascular system and contribute to weight loss. You will benefit from small doses of red wine, it is most effective to take resveratrol 1000 mg daily as a dietary supplement. combating damage from toxins in the atmosphere. The use of resveratrol accumulates collagen in the skin and keeps the skin firm and wrinkle-free.
The main benefits of autophagy come from the basic principles of its anti-aging action. Autophagy activates the process of rejuvenation of the organism, destroying old cells and promoting the development of new young cells. When the cells are under stress or are damaged, the effect of autophagy is disturbed.
Fasting and starvation of the organism leads to a stronger activation of atophagy and decomposition of damaged cells.
At the cellular level, autophagy helps by:
– removes toxins and proteins from cells associated with neurodegenerative diseases such as Parkinson’s and Alzheimer’s
– recycles proteins
– produces energy and building material for the repair of damaged cells and the construction of new young cells
– on a wider scale promotes the regeneration and health of the complete cell system
Autophagy can successfully treat cancer, a regulated diet combined with autophagy can reduce cancer activity.
Since all cancers actually start from mutated cells, autophagy itself can have a preventive effect on the possible development of cancer in the body. With the help of autophagy and the immune system, the organism has the ability to recognize and destroy cancer cells.
Researchers believe that the use of autophagy should be associated with other anti-cancer therapies and that outstanding results can be achieved in this way.
Over time, autophagy increases the interest of researchers in discovering the increasing benefits that the organism has from it. Research is expanding to various other areas.
For now, nutrition experts emphasize that autophagy is still an under-researched area and that much more information needs to be gathered to know what exactly amplifies it and what are all the positive aspects of this metabolic process.
In order for the organism to adapt to autophagy, it does not need to be immediate and extreme. it is best to gradually introduce fasting and exercise as a routine and get used to it over time.
You must consult a doctor if you are taking any medications, suffer from a chronic illness such as diabetes or heart disease, or if you are pregnant.
In the comments, share your experience with autophagy, ask a question or answer a question.