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Vitamins and minerals for cancer

Exploring the link between nutrients, metabolism and genetic sensitivity in the etiology of cancer is an important focus from a scientific and public health point of view. Since the etiology of cancer is multifactorial, it is necessary to study whether nutritional therapy, especially vitamins and trace elements, have a positive (preventive) or negative (higher risk) impact.

On the other hand, the evidence points to the fact that calorie restriction can reduce the occurrence of cancer, as in the study of Tannenbaum, which reports that in rodents, calorie restriction is positive in relation to the process of carcinogenesis. Therefore, the connection between is emphasized overweight , sedentary lifestyle and increased risk of cancer, especially colorectal, endometrial and breast cancer, which is explained by the ratio of hyperinsulinemia, elevated growth factors, estrogen and endogenous androgens.

Cancer is characterized by a progressive accumulation of mutations in the genome of the cell, where homeostatic mechanisms that determine the balance between proliferation and cell death are affected. Chemical oxidation is defined as the loss of electrons, while reduction is the gain of electrons. Therefore, it is understood that substrate oxidation is always associated with electron receptor reduction. The oxide reduction potential is therefore the redox potential that measures the flow of electrons involved in oxidation processes.

In aerobic beings, multiple chemical reactions with oxygen represent the most efficient mechanism of energy production, since they can generate intermediates or oxygen-reactive substances that accept electrons, form free radicals, unstable and reactive compounds with one or more unpaired orbital electrons. The isoform of oxidonitric synthase during the chronic inflammatory process can induce carcinogenesis, participating in the angiogenesis of tumor progression. The response of the host to this activity leads to the activation of the immune system, and with it the anti-inflammatory cytokines, tumor necrosis factor alpha and oxidant molecules. The human antioxidant system depends on some key nutrients: water- and fat-soluble vitamins, as well as trace elements. Oxidative DNA lesions are a crucial process in carcinogenesis, because they generate damage to nitrogenous bases, highly mutagenic modifications, which produce genetic instability at the sites of cell replication.

Diet and cancer: a complex relationship

The relationship between nutritional status, progression and cancer prognosis is based on the fact that both in clinical practice and in several studies it has been observed that well-nourished patients have a better prognosis and quality of life, emphasizing that malnutrition can negatively affect morbidity and mortality in cancer patients. in response to treatment, due to the toxicity that various antineoplastic treatments can cause, among the effects: nausea, vomiting, diarrhea, mucositis, xerophthalmia.

On the other hand, tumor products also act on the central and peripheral nervous system , causing psychogenic effects such as anorexia, depression and anxiety, tumor cachexia, metabolic changes, thinness, weakness, decreased protein synthesis, loss of functionality. Among the mechanical effects of tumors, obstruction and malabsorption are considered important, which can cause a lack of macro and microelements, and thus significant weight loss, regardless of sufficient intake.

Another important aspect to consider is the fact that specific antioxidants such as flavonoids, folate and vitamin D. may reduce the risk of developing cancer.

Hence the importance of the nutritionist, who must perform screening to measure risk and nutritional assessment to diagnose nutritional status, as well as food history to study the patient’s eating habits.

Research with vitamin C.

Wright and co-workers studied the genetic variants and their impact on the risk of gastric cancer, based on the strong biological evidence that ascorbic acid has in the stomach. The study found ascorbic acid in high concentrations in the juices and gastric mucosa in patients with chronic gastritis, while in patients with cancer the concentration was low. That describes that ascorbic acid neutralizes reactive oxygen and inhibits the formation of N-nitroso compounds. stomach, showing that ascorbic acid can inhibit cell proliferation and apoptosis in gastric cells;

It even seems that ascorbic acid can directly affect the growth of Helicobacter pylori. They conclude that common variants of the SLC23A2 gene directly regulate the active transport of ascorbic acid, which may have a positive effect on the risk of gastric cancer.

On the other hand, Legut et al. Presented results in which deficient levels of vitamin C and anacardiac acid significantly increased the cytotoxicity of the antineoplastic drug in melanoma compared with ammonium sulfate liposomes. Vitamin C and anacardiac acid protect normal cells from damage caused by antineoplastic drugs. The combined formulation of vitamin C, anacardiac acid and mitoxantrone shows favorable results in terms of cytotoxicity and cytoprotection.

Cherdintsev et al. Report that a nitrotriazole derivative called Sanazole, which is usually used in high doses to improve the effectiveness of radiotherapy, causes peripheral neuropathy in some patients, which is classified as neurotoxic. In view of this, they conducted an in vivo study in mice, in which they noticed that the use of ascorbic acid glucoside before the use of sanazole in cancer patients manages to protect the body from neurotoxic effects.

Glutathione system

The glutathione system is especially important for defending cells from reactive oxygen species (ROS). Reduced glutathione (GSH) reacts directly with radicals in a non-enzymatic reaction and is an electron donor in the reduction of glutathione peroxidase (GPk) catalyzed peroxides. medicine.

Mikirova et al., Meanwhile, point out that ascorbic acid has therapeutic potential when given intravenously (IV), because plasma ascorbate levels may mediate inflammation, which could increase healing in cancer patients, suggesting that this intravenous form is safe. and can be adjunctive therapy for clinical cancer care.

Study performed using 15 g IVC

The study was performed using 15 g of IVC ascorbic acid in a specific way in patients with different types of cancer, observing favorable results. for their part – point out that ascorbic acid has therapeutic potential when given intravenously (IV), because plasma ascorbate levels may mediate inflammation, which could increase discharge in cancer patients. that this intravenous form is safe and can serve as an adjunct therapy for clinical cancer care. The study was performed using 15 g of IVC ascorbic acid in a specific way in patients with different types of cancer, observing favorable results. which could increase discharge in cancer patients.

They suggest that this intravenous form is safe and can serve as adjunctive therapy to clinical cancer care. The study was performed using 15 g of IVC ascorbic acid in a specific way in patients with different types of cancer, observing favorable results. which could increase release in cancer patients They suggest that this intravenous form is safe and may serve as adjunctive therapy to clinical cancer care. The study was performed using 15 g of IVC ascorbic acid in a specific way in patients with different types of cancer, observing favorable results.

Mehdi et al. Presented important results showing that there is a significant increase in levels of advanced protein oxidation products (AOPP), malondialdehyde (MDA) and adenosine deaminase (ADA) in patients with multiple myeloma before treatment, compared to healthy subjects.

In contrast, total antioxidant capacity (TAC), glutathione, ascorbic acid (vitamin C), α-tocopherol (vitamin E), and antioxidant enzymes were significantly reduced. Therefore, biochemical changes caused by this type of cancer are evident.

Research with vitamin zinc

Christudoss et al., In their research, suggest that aspirin, vitamin C, and zinc may be administered separately to obtain a chemoprotective effect against preoplastic colon and carcinogenic colon progression in dimethylhydrazine (DMH) -induced rats. Therefore, the inhibitory effect is associated with maintaining colon tissue essential from zinc and zinc enzyme levels as close to normal as possible.

Because the effect of high doses of vitamin C as a cancer treatment is controversial, several studies have shown that vitamin C at a concentration of 0.25 to 1.0 mM in plasma, induced by dose and time, can inhibit cell proliferation in acute myeloid leukemia. . Treatment of cells with high doses of vitamin C results in an immediate increase in the content of intracellular glutathione S-transferase and its activity, followed by cysteine consumption.

These results indicate a new role of vitamin C in high concentrations as a modulator of sulfur-containing intracellular components, such as glutathione and cysteine. On the other hand, a clinical study reports a significant reduction in L ascorbic acid alternating with supplements in the treatment of patients with acute myeloid leukemia or myeloid dysplasia syndrome.

During the supplementation phase, patients received intravenous vitamin C daily prior to therapy, observing the in vitro behavior and sensitivity of leukemia cells to vitamin C, indicating that cancer cells are sensitive to vitamin C.

They conclude that although they accurately postulate specific mechanisms, vitamin C is difficult, however, they relate to the identification of genes or proteins that are specifically regulated by vitamin C in certain cellular phenotypes and this could improve the efficacy of cancer therapies.

In vivo study of Kontek et al.

In vivo study of Kontek et al. shows that vitamin C can cause a weak effect on DNA damaged by hydrogen peroxide and a positive effect on DNA damaged in HT29 cells (reduction of approximately 30%). They note that DNA damage was effectively repaired within 120 minutes after incubation in test cells that had one of the highest types of oxidative damage.

For their part, Paiva et al investigated the effects of vitamins C and E on tumors in xenographic mice with the sarcoma model (S180) in vivo. The result of the experimental study suggests that doses of 100 mg / kg of vitamin C and 400 mg / kg of vitamin E create a significant inhibition in tumor behavior. The encapsulation of anticancer drugs in the structure of liposomes protects the drug during its circulation and increases the accumulation of the drug in cancerous tissue, as well as its antitumor activity, while reducing the toxicity of the drug. Dominic’s study. and co-workers, propose a new drug loading method based on the pH gradient of vitamin C / ion.

The formulations are characterized in terms of parameters such as optimal external pH, time and drug-lipid ratio to achieve in vitro stability. In the specific case of epirubicin (EPI), its coencapsulation increases anticancer activity through possible synergistic effects reported by different groups of drugs with vitamin C without encapsulation. The method has another advantage which consists in enabling faster release by destabilization of liposomes at the tumor site, thanks to the very good solubility of EPI in vitamin C salts, as is observed in cryogenic transmission. This affects the drug release process and increases the anticancer activity of the liposome formulation. The antitumor activity of the encapsulated drug was confirmed (it inhibited tumor growth by over 40%, while it was shown that the drug that was not encapsulated did not have anticancer activity).

Vitamin E

Fat-soluble vitamin E., called tocopherol: alpha, beta, gamma and delta. Considered the main antioxidant found in the body’s lipid membranes, it protects polyunsaturated fatty acids from cell membranes from their oxidation by blocking free radicals. In addition to preserving carotenoids and selenium in a reduced state, favoring their antioxidant properties.

Its deficiency is characterized by hemolytic anemia, neuronal degeneration and reduction of serum creatinine with excessive losses in urine. Prolonged deficiency of this micronutrient causes musculoskeletal injuries and liver disorders. On the other hand, vitamin E poisoning causes nausea, headache, fatigue, hypoglycemia.

As for its effect on cancer, vitamin E plays an important role in reducing the neurotoxic effects of ciplastin. Vitamin E supplementation with 400 mg / day reduces the frequency and severity of neurotoxicity, and evidence suggests that vitamin E is assigned an important role, along with vitamin C, carotenoids, and folate, in the prevention of pancreatic cancer. While in the study of alpha tocopherol, beta carotene from the Study Group for Cancer Prevention, it was noted that no reduction in the incidence of lung cancer was found among male smokers after 8 years of dietary supplementation with alpha tocopherol or beta carotene. In fact, these tests shed light on the possibility that these supplements may do more harm than good. They also identified an association between vitamin A supplements and breast cancer risk, reporting a statistically significant incidence. Regarding complex B, they reviewed several studies, but did not find a link that supports complex B supplementation with both niacin and breast cancer.

Vitamin A-Retinol or carotenes, carotenoids

Vitamin A -Retinol or carotenes, carotenoids, are a fat-soluble vitamin with a recognized antioxidant effect in vitro. Carotenoids are absorbed in the small intestine and depend on the adequate absorption of fats, bile salts and pancreatic stereos. Its absorption is close to 80%, and then it is transported through the lymphatic system as a part of lipoprotein chylomicrons in the liver.

Its deficiency (serum concentrations <0.35 mmol / l) is characterized by: night blindness, xerophthalmia, Bitot’s spots, among others. Intoxication includes irritability, headache, anorexia, diplopia, alopecia, joint pain, liver disorders, bleeding. Among the antioxidant functions are: regulation of epithelial cell differentiation, inhibition of cell proliferation, increased immune capacity, inhibition of mutagenesis caused by physical carcinogens, reduction of nuclear damage caused by chemical and biological carcinogens. The strongest evidence regarding beta-carotene supplementation and lung cancer currently relates to the fact that high doses of beta-carotene can cause lung cancer in tobacco smokers.

Vitamin D

There are two forms of vitamin D in the body: D2, ergo calciferol and D3 hole calciferol. Vitamin D2 present in vegetables and vitamin formulations, D3 is synthesized in the body by exposing the skin to ultraviolet rays. Due to its characteristics, it is considered a hormone, with different functions from other vitamins, in addition to the fact that the body synthesizes it thanks to the sun’s action. Its activation to calcitriol begins in the liver and ends in the kidneys. Involved in bone growth, bone mineralization, and cell differentiation (cells of the immune and hematopoietic systems), it also acts as a medium to link a family of nuclear receptors such as steroids in general. It is a unique and specific nuclear receptor with direct transcriptional activity related to the response elements to vitamin D.

Because of these global effects and the immune system, including cell differentiation and proliferation, vitamin D is credited with a role in carcinogenesis and genetic polymorphism. Vitamin D deficiency has an epidemic prevalence in India ranging between 70% – 100% of the population, as cultural and religious practices do not allow adequate sun exposure as well as dairy consumption, and as a result people suffer from subclinical vitamin D deficiency, which favors high prevalence of osteoporosis, cardiovascular disease, diabetes, and cancer.

Due to the fact that mRNA receptors for vitamin D are detected in the human esophagus, they are assigned a regulatory role in the cell cycle, contributing to inhibition and differentiation in apoptosis of normal and transformed cells, where 25 (OH) 2D3, which is the active form of vitamin D3, contributes by protecting cells from turning into carcinogens. Significant evidence supports the anticancer role of vitamin D3 against breast, prostate, skin, and colon cancers, both in vivo and in vitro experimental models, and the most recent are those supporting Vit D3 metabolites to inhibit the growth and differentiation of esophageal cancer cells in vitro.

However, the evidence does not clearly show a link between vitamin D3 and the risk of esophageal cancer. In a study by Gui-Ling Huang et al., There is evidence of an association between high serum vitamin D3 concentrations and beta-carotene with a low risk of esophageal cancer. On the other hand, in the Pankaj G study, they point out in their hypothesis that the use of chemotherapy in colon cancer can cause changes in diet, such as the removal or reduction of dairy products as part of chemotherapy management due to induced diarrhea.

In addition, it has been observed that patients treated with this treatment do not absorb vitamin D due to subclinical mucositis, which is why these patients may need large amounts of vitamin D over long periods of time to achieve an appropriate serum level of 25 (OH) D. found that an oral formulation of 8,000 IU of vitamin D daily for 8 weeks was a safe regimen to correct vitamin D deficiency in cancer patients.

The response to such supplementation leads to the return of suboptimal to optimal levels in patients with prostate and lung cancer (with initial levels of 20-32 ng / ml), as well as in patients with colon and pancreatic cancer whose baseline levels are usually lowest (below 20 ng / ml). The impact of improvement in patient serum levels of 25 (OH) D, survival and quality of life should be investigated.

Another finding by Pankaj and co-workers is the association of obese cancer patients with vitamin D deficiency, compared with normal-weight cancer patients. Some of the proposed mechanisms explain the association between obesity and hypovitaminosis D, which, in addition to involving a lack of sun exposure due to physical inactivity, also refers to the sequestration of vitamin D in subcutaneous adipose tissue. Recently, such studies have suggested determining whether restoring and maintaining adequate levels of vitamin D may affect tumor control and survival.

Folic acid

Folic acid is soluble in water and its sources are fruits, dark green vegetables and seeds. People are not able to synthesize this vitamin, so it must come from dietary sources. Its bioavailability is higher as folic acid than as folate, because it is not conjugated and therefore more stable. Multiple mechanisms suggest that it has a preventive role in carcinogenesis, including molecular mechanisms such as DNA synthesis, repair, and methylation.

Marinos et al., Point out that even a study by nurses (NHS) showed that a diet high in folate reduces the risk of colon cancer or adenomas, but not when folate comes from a supplement.

It has been suggested that folic acid supplementation may be associated with increased adenoma recurrence and may be detrimental to those patients with a history of colon cancer. Therefore, it is recommended that multivitamins containing folic acid do not exceed 400 μg. It is necessary to emphasize that folic acid has nutritional properties and chemical structures similar to folate and folacin; it is a coenzyme that participates in the synthesis of nucleic bases, purines and pyrimidines to form nucleic acids, along with vitamin B, and in protein metabolism. Folate is important in DNA synthesis, so it somehow plays a role in carcinogenesis. This role is considered important, as the folic acid pathway is a natural antifolate drug such as methotrexate.

Therefore, in the treatment of cancer, they are harmful for both cancer cells and normal cells, which is why they cause the well-known side effects of these drugs. Folic acid deficiency results in megaloblastic anemia, leukopenia, anorexia, diarrhea, glossitis, weight loss, dermatological disorders.

Folate is thought to help prevent cancer by participating in the synthesis, repair and function of DNA. Folate deficiency can result in DNA damage which can lead to cancer. In contrast, other studies suggest that excess folate may promote tumor activation. Folic acid is involved in the metabolism of amino acids and is necessary for the methylation of nucleic acid. It is important to consider that one of the drugs that interferes with folate metabolism is methotrexate, which is known to be used to treat cancer. Its direct interaction is that it inhibits the production of the active form, tetrahydrofolate. In addition, methotrexate may have a toxic effect such as inflammation of the digestive tract, which in turn would affect oral intake.

Folic acid, in turn, can help reverse the toxic effects of methotrexate. However, it is known that small doses of methotrexate can reduce folate stores causing deficiency. In contrast, diets high in folic acid, as well as its supplements, can help reduce the side effects of methotrexate without reducing its effectiveness. Compared to the doses indicated as a supplement, they found that there was an increased risk when doses of folic acid greater than 400 μg / day were added.

Calcium

Calcium, an important macroelement in the processes of blood coagulation, neuromuscular excitability, nerve transmission and muscle contraction. It also plays an important role in bone and tooth mineralization, enzyme activation and hormonal secretion. Responsible for the transport of vitamin B12 in the gastrointestinal tract and necessary for the maintenance and function of membrane cells. Hypocalcemia is associated with the secretion of calcitonin by tumor C cells of the thyroid gland, sometimes the thymus and parathyroid glands, by reducing the concentration of calcium and phosphate in the plasma and by inhibiting bone absorption. Hypercalcemia is associated with parathyroid tumors.

Zinc

The most common trace element after iron. The composition of metalloenzymes with great antioxidant power, with a relevant role in cell growth and replication, in full maturation, fertility and reproduction, also in phagocytic, immune and humoral functions, as well as in taste and appetite.

On the other hand, zinc deficiency can alter protein synthesis by reducing serum levels of transport proteins such as albumin, pre-albumin, transferrin, affecting the availability of micronutrients. Deficiency can be caused by low consumption or large intestinal losses (diarrhea, drainage, etc.)

With cisplastin and diuretic therapy, it also occurs during chemotherapy with agents that promote mucositis.

Even low Zn levels correlate with higher mortality in cancer patients receiving high doses of antineoplastic drugs in chemotherapy, as occurs with bone marrow transplantation.

Zinc study

Chistudoss and co-workers report that zinc deficiency or excess appears to be involved in the development or progression of some types of cancer. In their experimental model, it is suggested that plasma zinc deficiency in tissue reserves and zinc-dependent enzyme activity are associated with the development of pre-neoplastic lesions, because such biochemical parameters decrease in proportion to the progression of colon cancer. as happens with bone marrow transplants,

Selenium

Selenium, a trace element that acts through selenium proteins, some of which are enzymes such as glutathione peroxidase. Its functions include the promotion of body growth, prevention of pancreatic disorders, liver necrosis, degenerative diseases of the white muscle and the appearance of Keshan’s disease (juvenile cardiomyopathy).

It is important for neutrophilic and polymorphonuclear cytotoxicity. An important biological role is its recognized antioxidant power, which is secondary to selenoenzymes (glutathione peroxidase, selenoprotein P, thioredoxin peroxidase, immunomodulatory iodothyronine deiodinase: optimization of cellular and humoral immune response by improving the phenomenon of lymphocyte proliferation and phagocytosis.

During the state of hypercatabolism, a deficit in the nutritional status of selenium is created. Reactant in the acute phase. In critical illness (characterized by an inflammatory condition with oxidative stress), serum selenium levels fall early, with an inverse relationship between these events and mortality.

Manzanares suggests a selenium supplement of 450 ug / day for 14 consecutive days. For their part, Heiland and colleagues suggest a selenium intake of 100 μg / day in critical patients, while in large burns it should be 375 μg / day. They state that the dose of selenium is associated with a reduction in mortality in critically ill patients from 500 to 1000 mg / day.

Scientific opinion regarding the relationship between selenium and cancer risk is very mixed. It was initially seen as a possible carcinogenic system during the 1940s, and then as a possible protective agent between the 1960s and 2000s. More recently, controlled studies have found no effect on cancer risk, but suggest low dermatological dose and endocrine toxicity; in animals they indicate both carcinogenic and preventive effects.

Epidemiologically, the evidence reports that there are no cancer-related preventive effects in increasing selenium doses in healthy individuals, but if the risk of causing disorders and diseases of another nature, the form of organic or inorganic presentation may be dramatically different from these biological effects. Selenium deficiency is associated with cancer risk; it is even considered mineral chemotherapy.

Selenium testing

336 patients (black and white race) with Se supplementation and placebo group were examined. After supplementation with Se, a direct association between Se and GSH in the blood was observed, resulting in a higher in whites than in blacks with p <0.01. (44). Se can be effective in preventing lung cancer, especially in people with low Se levels, however it should not be used as a general strategy. It reduces the level of toxicity in chemotherapy and radiotherapy in the same way.

Conclusion

Because cancer treatment and the type of cancer diagnosed affect the patient’s nutritional status, the nutritionist plays a key role in its progression and treatment. Antineoplastic treatments can produce micronutrient deficiencies, hence the importance of nutritional therapy, especially the studied micronutrients, in order to reduce the toxicity of such treatments in a timely manner and thus improve tolerance to them and the quality of the patient’s oncological life.

Colloidal minerals

In our society, people are either overweight or malnourished. Why is that? A study of the western population reveals that people consume 8 times more fat in the body than they need. They make up 42% of the total calorie intake, twice as much protein as we need, and incredible amounts of simple sugars. The real irony is that our body is in constant deficit with vitamins and minerals. Our body needs a sufficient amount of vitamins and minerals to function normally. In the absence of minerals, various health problems occur, such as bleeding, dysfunction of the immune system, and organ dysfunction.

Mineral diversity

About 73 minerals that our body needs to be supplied with regularly. Of these 73, only 10 are with the recommended daily dose. These minerals that our body uses every day are calcium, magnesium, zinc, manganese, copper, iodine, chromium, selenium, and molybdenum. Our body certainly requires more than these 10 minerals. Calcium, for example, is the most abundant mineral in our body and is most abundant in our skeletal system. Calcium deficiency not only causes bone problems but also affects the heart muscle.  Magnesium is the fourth most abundant mineral in our body that keeps our cardiovascular system healthy. Magnesium deficiency is closely related to hypertension’s appearance and an increase in cardiovascular problems.

Mineral transport

Enteral pathways deliver minerals to our bodies.  They are usually in simple salts dissolved in water or chelated form. Each of these forms ensures the mineral’s bioavailability so that it can be easily digested and absorbed by the body. Minerals in their basic biological form are tough to pass through the cell membrane.  Our cell membrane is a phospholipid bilayer that is hydrophobic internally and hydrophilic externally. A hydrophobic substance will pass through the cell membrane rather than a heavy basic form of molecules. This creates a code absorption problem of the minerals above basic form. It is important to note that not all mineral supplements are the same. Since they come in different forms, we can conclude that they are absorbed differently in our bodies. You can take calcium in the form of calcium citrate or calcium carbonate. Although both types supply calcium, both will be absorbed to varying degrees by the body, representing a large difference in bioavailability in these seemingly the same two types of calcium salts.

Colloidal minerals

What is the best form of mineral supplements? Nature gives us minerals in different forms and from different sources. But not all sources are equally useful for our body. In some cases, the source may contain heavy metals, or the concentration of minerals may be very high to be considered toxic to our body. Colloidal minerals are gaining an increasingly popular role as a leading product in the dietary supplement industry.  For this reason, we will consider the role of in a little more detail colloidal minerals in the human body. Milk is an excellent example of a colloid; it is water with insoluble proteins suspended in a liquid. Colloidal minerals refer to a type of mineral suspended in water. They represent microscopic particles that provide a larger surface area and the possibility for better digestion and better absorption. Their shape varies depending on the condition of the tablets or pills, which deliver minerals in the form of lymph, which requires solubility to varying degrees and varies with the surface area and the number of minerals that the body will absorb.

How colloidal minerals are formed

Colloidal minerals in nature are obtained from the line and the rocks, which, when mixed with water, give their basic shape. Because they come from clay or rocks, not all rocks and clays are in the same shape; some of them may contain heavy metals or, in some cases, radioactive particles. The only logical solution is to obtain colloidal minerals from an organic source, i.e., from shales and clays obtained by organic decomposition. Plants take their mineral needs through the roots, and root serves as an excellent natural filter.  Collidine minerals obtained from clay or shale are an excellent source of many minerals. It has been determined that minerals from rocks and clay, from an inorganic source, are absorbed in the body. Organic colloidal minerals provide a naturally chelated form. Chelated minerals with amino acids have a 50 to 60% higher chance of being absorbed into the body. The acidification of our body also increases this process. The natural pH value of organic colloidal minerals is between 3 and 4, maintaining the chelated form of these minerals.

The role of collodion minerals

Colloidal minerals are a good source of various types of essential minerals. These include calcium, zinc, boron, magnesium, iron, boron, manganese, copper, illicium, iodine, chromium, vanadium, molybdenum, selenium, germanium, strontium, nickel, tin, cobalt, cesium, rubidium, gallium, and many others. Iron is known for its important role in synthesizing red blood cells and zinc to modulate the immune system, fighting inflammation and the wound healing process. Boron is essential for hormonal metabolism, immune function, and cardiovascular health.  Calcium is essential for bone and cartilage growth. Iodine is important in the synthesis of thyroid hormones. Chromium is used to metabolize blood sugar. Vanadium has anti-cancer properties as well as molybdenum and cesium.

By including supplements of colloidal minerals, we will provide our body with the necessary microelements that are necessary for the proper functioning of organs, as well as the normal functioning of the immune system, which is the best defense against external threats such as infections and internal threats such as cancer cells.

Zinc – How it can improve your health

Zinc is an essential mineral whose deficiency can be seen in your diet and your body’s daily functions and behavior. This mineral is present as an ingredient of more than 200 enzymes in the human body. Cells need zinc for replication to regenerate the organism and for many other purposes related to microcellular processes and their uninterrupted functioning.

High levels of zinc in the human body are found in white blood cells, red blood cells, bones, pancreas, kidneys, liver, prostate, and cornea.

Zinc (lat. zincum) is a chemical element with the symbol Zn and atomic number 30. Zinc is considered a transition metal 12. groups, but among them, he occupies a special

Zinc plays a significant role in the body’s defense system

immune system

It is of fundamental importance for creating white blood cells that are the carrier of the body’s immune and defense system. Scientific teams of researchers have determined that the intake of zinc as a supplement reduces the impact of cold on the body and, at the same time, the occurrence of many diseases due to cold. Additional research results show that zinc can reduce pneumonia in children under 5 years of age. You can read more information about the immune system in the text Immune system and the body’s defenses.

An amazing remedy for acne and pimples

Zinc reduces swelling on the skin that has been found to be caused by hormonal disproportions in the body. Daily zinc intake reduces acne, pimples and skin ulcers.

Zinc is essential for skin health

The accumulation of large amounts of free radicals in the body often causes many human health problems. If free radicals are not adequately removed from the body, they lead to very early aging, cardiovascular problems, skin problems such as stretch marks, dermatitis, dandruff, psoriasis, eczema, vitiligo, white marks under the nails, etc. Antioxidants from zinc serve to regulate free radicals, and with their help, this element solves many of the above-mentioned skin problems, in the absence of sufficient zinc, the skin cracks and wounds form.

Women who want to stay pregnant need to take zinc because of its ability to regulate and return hormones to normal limits and values, which is of primary importance during their reproductive system and fertility.

Increases testosterone levels in the blood

A sufficient amount of zinc in the body helps increase the level of testosterone in the body, which is vital in the sexual life of every man.

It has a preventive effect on hair loss, fertility problems, and lack of sexual desire in men. Zinc also affects and inhibits the female hormone’s development in the male body.

Increases the concentration and activity of sperm in men

zinc mineral

According to modern research studies, in men who have reduced zinc levels, depression of sperm values is pronounced, while in those who have sufficient concentrations, exceptional activity and quantity of sperm have been established, as well as very pronounced potency. Men can increase the value of sperm by daily intake of 50 mg of zinc. Inactive sperm can use zinc as a dietary supplement to solve this problem.

Zinc helps with normal prostate function

Zinc significantly reduces the chances of prostate enlargement and malignancy. Disorders such as prostatitis (inflammation of the prostate), prostate malignancy, and other disorders related to male infertility are sure indications of zinc mismatch in the body. Erectile dysfunction is also involved in these disorders due to the disproportion of certain male hormones, such as deficient testosterone levels.

Zinc restores vision

zinc for sight and eyes

The eyes and eyes need huge amounts of zinc to function normally. The eye’s retina is rich in zinc and one of the tissues in the body that relies most on zinc.

Zinc supplements stimulate the sense of sight and correct some problems caused by its deficiency. Researchers have proven that visual impairment of moderate macular degeneration can be treated by increased zinc intake in the body.

Zinc stabilizes blood sugar levels

Zinc is among the three most important ingredients for blood sugar levels (the other two are chromium and niacin). In combination with insulin, these three are agents for glucose factor tolerance. Zinc represents a brake on blood sugar levels. People with diabetes suffer from zinc deficiency in the body. In case of zinc deficiency, it is necessary to take about 150 mg of zinc every day to return this element to normal.

Zinc develops bone structure

zinc for bones

Zinc affects the processes in the brain and repairs many damages in it. Simultaneously, it has a preventive effect against stroke, Alzheimer’s disease, and other similar disorders and diseases.

Zinc, together with calcium and magnesium, acts as a cocktail of calming elements on the body, and these three elements interfere with unnecessary brain activities. This cocktail also has a hypnotic effect on neurotransmitters. Zinc positively affects the intellectual work of men and women. Zinc directly affects the regeneration of fibers in the brain.

Zinc affects the assimilation of calcium in teeth and bones.

Recommended dosage of zinc

By the recommended dietary intake of this compound, the proposed daily dose of zinc is regulated by the person’s age.

For babies from 0 to 6 months, an intake of 2 mg of zinc per day is suggested.

For babies from 7 months to 3 years of age, an intake of 3 mg of zinc per day is suggested.

For children from 4 years to 8 years of age, the intake of 5 mg of zinc per day is recommended.

For children aged 9 to 13, an intake of 8 mg of zinc per day is recommended.

A daily zinc intake of 11 mg for men and 8 mg for women is recommended for people over 14 years of age. Higher concentrations of zinc are regulated for women who are pregnant.

Summary

Since zinc is lost during grinding and also during the preparation of food such as cooking and baking, it is very likely that at some point, there may be a deficiency of this mineral in our body.
 
Regardless of taking a balanced and regulated diet, if you use therapeutic prescriptions, the use of zinc as a supplement in your daily diet is definitely included.
 
Its use also lies in the property of many drugs to reduce the level of zinc in the body. Please consult your doctor before using any zinc dosage and its use and before use.

MSM and its impact on cancer

Millions of people a year discover that different cancer types have developed in their bodies. Some are deadly, while others are not. MSM or Methylsulfonylmethane has been analyzed in the last few years, and this preparation has shown amazing results in people who have suffered from some malignancy. If you live with cancer or know someone who has it or simply wants to prevent cancer in your body, then MSM powder can be absorbing for you. I will give you answers to some questions that can be very interesting and are directly related to the origin and development, maintenance of cancer in the body.
MSM can be successfully used with artemisinin to destroy cancer cells. Artemisinin is extremely successful, and in many countries, its anticancer effect has been tested for many years. You can read more about artemisinin in the article Sweet wormwood plant cure for tumors and cancer.
Combined with the DMSO preparation, which hydrates and increases the intake of substances in the body, MSM gives better results.
Please read the article DMSO and its anti-cancer properties.

How does MSM affect cancer?

cancer informationMost carcinogenic diseases prefer an organism with high acidity or high Ph value. As cancer develops and grows, the body becomes more and more acidic. MSM helps the body maintain the body’s Ph value within normal limits. With MSM, the organism is detoxified. Since many cancer cells cannot survive in an organism that does not have a high Ph value, a large number of cells die.

Does MSM cure cancer?

MSM does not cure cancer in the true sense of the word, and it rather reduces the impact of this disease on the body. It should be noted that since we take in large amounts of inorganic foods, there is also not enough intake of sulfur in the body. By adding quality MSM to our diet, we get a sufficient amount of sulfur that helps the normal functioning of our body and, at the same time, increases the permeability of cell membranes because sulfur is necessary for this microcellular function. Also, our body will have enough sulfur to fight cancer.

Can other preparations be taken with MSM?

You can take MSM with literally all other vitamin supplements or medications without fear of side effects. Many nutritionists include vitamin C and vitamin B12 in their MSM program. How much MSM you take depends on your age, body weight, and other conditions.

How does MSM affect cancer cells?

MSM is an amazing form of sulfur. As such, it affects cancer cells, as I mentioned earlier so that the cell membrane is more permeable. The permeability of a cancerous cell’s cell membrane is very low due to the protein coat. Therefore, cancer cells cannot release large amounts of toxins that maintain their structure and make deformed DNA, causing disrupted microcellular processes such as disrupted protein production or low production of ATP molecules.
You can read more about cancer cells’ processes in the article How cancer develops.
MSM helps in the acceptance of drugs and their implementation in cancer cells. Chemotherapy drugs are also included. By increasing the permeability, the cells oxidize, which is very good. MSM also increases collagen production, which stops the spread of cancer. MSM stops and destroys cancer directly and indirectly.
You should note that MSM very easily bridges the blood-brain barrier. When treating brain cancer, MSM is essential to achieve maximum effect and results.

How is MSM related to oxidation?

MSM oxidizes the blood. When blood is oxidized, it easily delivers oxygen and other substances to our cells. This increases the large intestine’s capacity, takes in oxygen, and disinfects the blood.
MSM will be your hidden weapon in the fight against a vicious disease called cancer. You can also use it preventively. In that case, the whole organism’s complete performance is improved by preventing the occurrence of many other diseases.
MSM can also be combined with a very successful treatment method with artemisinin. For more information about artemisinin, you can read the Artemisinin derivative of sweet wormwood and its growing importance in medicine. You can read more information about this preparation in the article Sweet wormwood use.

Selenium in the fight against malignancy

Selenium performs a significant role in several processes in the body. Even though it is present to a greater or lesser extent in every cell of the body, specific areas that are very rich in selenium are the kidneys, liver, pancreas, and spleen.
Selenium deficiency in your body can cause the following problems: cataracts, nail deformities, heart problems (increased heart rate), muscle cramps, slow growth, malignancy.

A diet rich in selenium

selenium
Therefore, your diet must contain foods that are rich in selenium. However, if you have a selenium deficiency, then some supplements that contain increased selenium concentrations are recommended. Most doctors today support the consumption of dietary supplements with selenium to achieve optimal levels of this mineral in the body. Recommended doses of selenium are as follows:
55 mcg every day for women
70 mcg every day for men
Patients suffering from some malignancy should consume 400 mcg of selenium.

The role of selenium in the fight against malignancy

hrana bogata selenom
Increasing the level of selenium in the blood reduces the risk of developing malignancy, but also, this compound plays a vital role in the treatment of malignant diseases.
Selenium is an integral part of several selenoproteins that play a significant role in several critical processes: conception, metabolism of thyroid hormones, DNA production, protection against oxidative damage, and protection against infection.
Researchers controlling the disease and its development, transmission, and origin have concluded that there is a strong link between selenium levels and the development of several types of malignancies, including malignancy of the bladder, colon, prostate, stomach, skin, lungs, and esophagus.

Statistics and research

Existing statistics show that people who had the maximum allowable concentration of selenium in their blood were 31% less likely to develop malignancy than people who had lower levels of selenium in their blood, and also had a 40% lower death rate in people who already have some form of malignancy compared to those with lower levels.
The US FDA announced in 2009 on its official website that “Selenium can reduce the risk of developing specific types of malignancy.” This certainly represented a leap in popularity for this biological mineral.

Sodium selenite

In the human body, various forms of individual compounds are used in different levels of concentration, consumed in a mixture with various types of proteins. Each configuration of compounds has its own characteristic set of objects. It should be emphasized that the 3 best configurations of selenium for the avoidance and treatment of malignancies are: sodium selenite, L-selenomethionine, and selenium menthyl L selenocysteine.
Perhaps the greatest dynamics in the destruction of cancer cells has inorganic sodium selenite, and its actions are as follows, which are explained and investigated in these studies:
Study of the effect of sodium selenite on induced apoptosis of human cervical cancer cells
Sodium selenite reduces oxidative DNA damage in BRCA1 mutation.

And other research related to sodium selenite.

Namely, sodium selenite has a very pronounced ability to create oxygen molecules that attack exclusively mitochondria that form in cancer cells. The specific protein BCL-2 is present in cancer cells, which prevents apoptosis. Sodium selenite usurps this protein and activates apoptosis. Sodium selenite also enhances the presence of the antioxidant enzyme glutathione peroxidase in healthy tissue by stimulating its activities which are as follows:

Killing cancer cells

selenium protiv kancera
Protecting healthy cells, repairing DNA sequences, and strengthening the immune system
The above actions are part of the treatment that harmoniously manages malignancy development.
During the first part of 2009, German scientists from St. Josef Hospital in Wiesbaden discovered that men who suffer from benign prostatic hypertrophy had reduced selenium levels in their blood.
Another study in 2009 proved that selenoproteins have dominant antioxidant and anti-inflammatory properties to inhibit prostate, colon, and rectal malignancies.
In March 2009, the Pen State College Cancer Research Clinic published a statement stating that combining vegetables such as cabbage, cauliflower, and kale with selenium added an even more effective effect on melanoma.

Chief researcher Professor Gavin Robertson states:

“Decreased concentration of selenium in the body of cancer patients is directly associated with the appearance of metastases.”
The professor also stated: “In research on prostate cancer and melanoma, it was determined that the protein AKT 3 matures and that its development is motivated by the presence of estrogen. It should be emphasized that there are no drugs that stopped it from developing, so the malignancy itself progresses. However, it has become apparent that selenium weakens the AKT 3 protein. “
In conclusion, in 2012 (American Journal of Clinical Nutrition), researchers from the Department of Nutrition at Norwich Medical School made a statement about selenium’s effects in preventing prostate malignancy. Their target of the investigation was the control of plasma aggregates of 13,254 actors and 5007 prostate malignancy cases. The relationship between plasma/selenium and prostate indicates that the risk of developing prostate cancer is reduced with levels up to 170ng / ml.

Selenium testing

In various studies looking at blood selenium levels in various people from different parts of the world, decreased selenium levels have always been associated with high malignancy levels.
In 1984, scientists from Kuopio University in Finland tested the blood on 8,000 men and women. In the following years, the development of malignancy was noticed in 128 respondents. When blood control was performed on people in whom the development of malignancy was not noticed, a deficiency was determined selenium. It was concluded that people with lower selenium levels are 3 times more likely to acquire malignancy. This phenomenon is primarily expressed in malignancies of the blood and colon.
Researchers performed one of the most significant experiments from the Group for Nutritional Preventive Action against Cancer (effects of selenium and its use in people with skin cancer) in 1996. In the same study, 500mg capsules enriched with 200 mcg of selenium were made, which patients consumed daily. The total number of respondents was 1312. It has been proven that in 17% of the cases, there was a decrease in mortality. In 37%, the incidence of malignancy was reduced.
Tests were also performed on the inhabitants of China, where there are areas rich in and poor in selenium and its intake during the diet. The investigation proved that people who do not consume selenium have a 20% increased probability of developing some form of malignancy.
In France, a seven-year SUV Max study involving 17,000 subjects who consumed vitamin C, E beta carotene, along with zinc and selenium, found 37% less chance of developing malignancy.

Glutathione selenium and chemotherapy

Glutathione peroxidase is a selenium-dependent enzyme, and 35 selenoproteins are involved in its functions. Studies have shown that inorganic selenium forms are less absorbed into the body than organic forms.
The drug Cisplatin used for chemotherapy can reduce selenium in the body. Numerous studies have stated that selenium can reduce the harmfulness of Cisplatin to a healthy part of the body.

Magnesium chloride application and medicinal properties

Magnesium chloride has the ability to accelerate cellular activity and thus the metabolism of the entire organism. Magnesium, a key element in producing many enzymatic reactions at the cellular level, becomes very effective in fighting infections when combined with chloride.

What sets it apart from other elements is that magnesium chloride helps the immune system fight cancer naturally. Since this mineral is filtered in the kidneys, it is not uncommon for many people to have a magnesium deficiency in the body.

Studies have shown that magnesium chloride helps the body strengthen the immune system. After taking this preparation, the body itself accelerated cancer cells’ identification and destruction. Magnesium chloride not only helps destroy cancer cells it also revitalizes patients. Cancer patients.

What exactly is magnesium chloride?

From a chemical perspective, magnesium chloride is the two elements, magnesium, and chlorine, that have formed the bond. The molecular formula is MgCl2, which means that two chloride ions form a compound with one magnesium ion. The two substances form a salt lattice, so their structure is a lattice.

When obtaining magnesium chloride from nature, seawater or saltwater springs are used as sources. For example, seawater was evaporated to give a crystalline substance. In this regard, magnesium chloride is still combined with table salt, so the table salt must be removed. In the end, pure magnesium chloride remains.

It is prevalent to use it to produce magnesium oils or baths. But it is also popular for consumption and therefore as a dietary supplement because the body can absorb it well in this form.

Function of magnesium in the body

Entire books could be written about the functions of magnesium in the body. The fact is that life without magnesium would not exist because the most important bodily functions would not function.

Magnesium chloride can be used to allow our body to perform the following functions, for example:

  • Necessary for the formation of bones and teeth
  • great influence on the transmission of stimuli between nerves
  • Adrenaline release
  • It activates over 300 metabolic enzyme
  • Blood clot inhibitor

It was just a short list of magnesium-dependent bodily functions. The most well-known is probably the transmission of stimuli between nerves because if this function does not function properly, muscle spasms can occur.

As you can see, it is an essential substance for our lives. We should make sure that we consume enough magnesium every day, namely at least 300-400 mg. Women should use it a little less than men.

How can magnesium chloride be used? – general use

when bathing

Magnesium chloride can be used and consumed in various ways. Different methods of application bring different benefits. For example, it can be applied to the skin with magnesium spray, but it can also be dissolved in water and drunk.

To give you a better overview, we will show you the most common application methods, including tips.

External use

If you prefer the external application of magnesium, you can choose between magnesium oil or a bath. You can use the baths by dipping your feet or lying in the bathtub.

Magnesium oil

The production of magnesium oil is not rocket science. To do this, dissolve approximately 3 – 3.5 g of magnesium chloride in 100 ml of water. You can then keep the mixture in a glass or fill it into a spray bottle. It is suitable for the so-called transdermal application, i.e., application to the skin, which is supposed to absorb magnesium into the body.

If you can’t mess around at home, you can buy magnesium oil. There are different versions, with or without a sprayer.

Feet or bath

Due to its good solubility in water, magnesium powder can be used in a bath or foot bath. Foot baths have a very relaxing effect due to the heat and can burden your back like problems and fatigue.

For a foot bath, put a few teaspoons in a wide bucket or foot bath and fill it with warm water. Mix the water so that the magnesium dissolves and keep the feet in the footbath for 20-30 minutes.

If you want to take a bath more, fill the tub with warm water. Then add about 500g – 1000g of powder. It will dissolve quickly. You should lie in the volume for about 20-30 minutes.

Magnesium chloride as a beverage

With the help of magnesium chloride, a drink can also be made. For this, you need magnesium chloride hexahydrate. This is a form that you can usually buy in pharmacies.

It is recommended to mix approximately 30 g with one liter of water and drink 50-100 ml twice a day. The dosage depends entirely on how well your body can tolerate magnesium chloride. If you get diarrhea, the dosage was too strong. It can also have a laxative effect.

Magnesium chloride absorption

magnesium chloride

How much can magnesium chloride be very easily absorbed through the skin? And in our case, we made a DMSO solution or used it as a bath salt, and this mineral can very easily reach metastasis. One of the most deadly cancer types, pancreatic cancer, is extremely difficult to operate on. Also, Mesothelioma is a type of cancer that is difficult to notice because it manifests and shows up only when it begins its cycle of spreading or metastasizing. During the use of magnesium chloride in clinical studies, it was concluded that these two types of very deadly cancers are withdrawn. Magnesium chloride has also been shown to be effective in other cancers as an activator of the immune system.

Magnesium chloride testing

In 1915, a French surgeon Professor Pier Delbet tried to find a solution that would clean the wounds because he noticed that classic antiseptics affected the wound tissue and accelerated the infection instead of preventing it.

He tested several mineral solutions and found that magnesium chloride not only does not destroy tissue but also has an exceptionally positive effect on leukocyte activity and phagocytosis. It proved to be a perfect solution for treating external wounds.

Dr. Delbet performed many “in vitro” and “in vivo” experiments and concluded that magnesium chloride is not only great for external use but that when used orally, it is an excellent activator and stimulator of the immune system.  He called the effect of this preparation cytoplasm. In some studies, magnesium chloride increased phagocytosis by 300%.

Dr. Delbet also discovered that oral use has a perfect effect on people and the entire human body.  Therapeutic use of this preparation is successful for a long list of diseases.

Use during treatment

Magnesium chloride has proven to be very successful in treating colitis, anginocolitis, Parkinson’s disease and tremors, muscle cramps in the nervous system, acne, eczema, psoriasis, warts, itchy skin of various origins. This preparation strengthens hair and nails, has a good effect on impotence, prostate hypertrophy, improves circulation, and affects allergic diseases, asthma and urticaria, and many other diseases.

Prof. Delbet also researched the relationship between magnesium and cancer. During clinical trials, he discovered that magnesium chloride has a powerful preventive effect on cancer development and successfully treats several pre-cancerous conditions such as leukoplakia, hyperkeratosis, and chronic mastitis.

Cancer and the immune system

Epidemiological studies have confirmed Dr. Delbet’s claim. In regions where the soil is rich in magnesium, a smaller number of people who have cancer have been recorded.

During the research, magnesium chloride’s solution also slowed down the development of cancer cells.

In 1943, another French doctor, A. Neveu, conducted several studies on magnesium chloride effects on diphtheria. It has been established that the use of magnesium chloride alone eliminates the symptoms of diphtheria in just one day.

He made an immune-stimulating serum based on magnesium chloride and found that all patients suffering from diphtheria were cured within one day without any contraindications. Since magnesium chloride does not affect bacteria, Dr. Neveu found that magnesium chloride has a stimulating effect on the immune system and can be used against viral diseases for that purpose. So with this preparation, he started treating some polio cases with excellent results.

Enemies of magnesium chloride

Soon these two doctors, due to their great success, gained a handful of enemies; there were professors, medicine, and academy with heads and beards, all intending to develop a new business of vaccinating the population and developing vaccines.

Dr. Neveu was not constrained by the fact that the entire medical intellectual elite rejected his scientific work. On the contrary, he continued his research with even greater intensity. He made amazing results in pharyngitis, hoarseness, colds, flu, asthma, bronchitis, broncho-pneumonia, emphysema, whooping cough, smallpox, rubella, mumps, scarlet fever, food poisoning, gastroenteritis, ulcers, asepsis, postpartum fever, and osteomyelitis.

Use of magnesium chloride

magnesium chloride oil

In the following years, the indications of the very healing effects of magnesium chloride do not end with these two French scientists’ work. Magnesium chloride is successfully used in asthmatic acute attack, shock, herpes zoster, acute and chronic conjunctivitis, optic neuritis, rheumatism, and many allergic diseases.

The use of magnesium chloride should be 25 grams in one liter of liquid.

Adults and children over 5 years 125 ml

4 years old children  100 ml

3 years old children  80 ml

1-2 years old children  60 ml

Over 6 months, children 30 ml

Under 6 months  children 15 ml

These doses are taken orally. Magnesium chloride has a laxative effect, so that diarrhea may occur in the first days of therapy, especially at high doses, but this is not a reason to stop therapy. The taste of the solution is not very good, so that you can add a little fruit juice from grapefruit or lemon.

In chronic diseases, 2 of the above doses are given daily for a longer period of time, several months at least and maybe several years.

In acute diseases, the doses are given every 6 hours or every 3 hours in severe diseases, then reduced to 8 hours and then to 12 hours as the condition improves.

As a preventive measure, magnesium chloride can be taken in one dose per day.

Magnesium chloride is more easily absorbed and used by the body

Due to its clinical and pharmacological mode of action and lower tissue toxicity compared to magnesium sulfate, magnesium chloride is the preferred form of magnesium because it is more easily assimilated and therefore more bioavailable. It makes it easier for the body to absorb and use it. On the other hand, magnesium sulfate is more difficult to absorb. Magnesium sulphate is also excreted faster than magnesium chloride via urine and kidneys. For that reason, magnesium sulfate should be taken much more and more often in order to achieve the same result.

It can be tempting to go to the nearest drugstore and buy Epsom salts for night relaxation. But if you really want to effectively reduce stress, opt for a good night’s sleep, magnesium bath flakes and oral magnesium are better choices.

Magnesium – Discover the most powerful mineral for relaxation

Magnesium helps in the treatment of very severe symptoms of illness and disease. This mineral is a potent secret weapon for treating diseases in practice. Half of the world’s population has a reduced amount of magnesium in the body.

Magnesium is an antidote to stress, and it is generally known as a relaxation mineral, which can also improve the quality of your sleep.

Many doctors are not familiar with this mineral’s capacity, and therefore it is not used sufficiently in conventional medicine.

Many doctors use it in very severe conditions, such as a life-threatening form of arrhythmia. Magnesium is then given intravenously. Also, when pregnant women come with high blood pressure are given continuously in high doses of intravenous magnesium.

You do not have to be hospitalized to benefit from magnesium. Start taking magnesium as a regular dietary supplement today.

Magnesium mineral for relaxation

Magnesium is a relaxing mineral. Whenever you feel nervous, moody, or irritated, you can be sure that you lack magnesium in your body.

This essential mineral is a key factor for over 300 enzymatic reactions in the body and can be found in all tissues in the body, but it is mostly found in bones, muscles, and the brain. Your body’s cells must produce energy and many other chemical processes such as stabilizing the cell membrane and helping relax the muscles.

For that reason, the list of disorders and diseases associated with magnesium is longer. Specifically, about 3,500 symptoms associated with a magnesium deficiency have been reported.

Although this mineral is ignored because it is not a medicine, it is more healing than many medicines for various diseases and disorders. Thus, it is also used in hospitals for symptoms such as arrhythmias and decreased heart activity.

Magnesium deficiency

If you do not have enough magnesium in your body, you may experience some of the following symptoms: muscle cramps, insomnia, nervousness, irritability to loud sounds, anxiety, autism, angina, palpitations, constipation, headache, migraine, fibromyalgia, asthma, kidney stones, diabetes, osteoporosis, high blood pressure, menstrual pain, swallowing problems, reflux.

Magnesium deficiency is also associated with inflammation in both the body and high CRP levels.

In our society, magnesium deficiency is a huge health problem. According to established standards blood measurements, serum, and magnesium levels, 65% of people need to ingest higher amounts of magnesium, and about 15% of the entire population has a chronic problem with magnesium deficiency. So almost all people have insufficient levels of magnesium in the body.

But that’s not the end; testing serum magnesium levels in the blood is not such a reliable method to determine the level of magnesium in our body and establish a drop in levels. For this reason, magnesium deficiency can be much higher in many.

The reasons can be various. Many of us eat foods that do not have sufficient magnesium levels, and that is refined foods or foods that are artificial, modified, and based on white flour, meat that does not have any magnesium.

When was the last time you ingested seafood, nuts, greens and seeds?

seafood

The magnesium level in the body is reduced by consuming alcohol, salt, coffee, stress, chronic diarrhea, menstruation, diuretics, the use of antibiotics, and the presence of parasites in the body. A study of people affected by the war in Kosovo exposed to chronic stress found a high magnesium deficiency.

One of the reasons is that magnesium is difficult to absorb and easily lost in our body. To be sufficiently absorbed in the body, we must take enough of it, and we must also take enough vitamin b6, vitamin D. and selenium.

How to increase magnesium levels?

The lack of this very affordable and cheap mineral creates great health problems. It causes severe diseases in the entire world population, although many are not aware of it. Some disorders can be taken away by hand. Here’s how:

Reduce your intake of coffee, Coca-Cola, salt, sugar, and alcohol

Learn how to relax

Check with your doctor to see if your taking medications are causing magnesium loss.

Start taking magnesium-rich foods into your body.

Take magnesium dietary supplements. It should be taken into the body about 300 mg per day, which is recommended by the World Health Organization.

Some people need a higher intake of magnesium due to their condition.

Most people need between 400 mg and 1000 mg per day, which is because magnesium is not completely absorbed in our body.

Magnesium citrate, magnesium taurate is best absorbed, magnesium glycinate, aspartate, magnesium chloride

Avoid magnesium carbonate, sulfate, gluconate, and oxide. The body poorly absorbs these forms of magnesium.

Negative effects

Side effects due to high magnesium intake are diarrhea which can be avoided if you use magnesium glycinate.

It is best to take magnesium with other minerals as a multi-mineral supplement.

Use warm baths with bitter salt or magnesium sulfate. It is a good way to absorb sufficient magnesium amounts through the skin.

People with heart and kidney disease can take magnesium only under the supervision of their doctor.

Magnesium glycinate – Health benefits and uses

Magnesium glycinate is a vital nutrient needed to keep the body healthy. It is essential for many bodily processes, including regulating muscle and nerve function, blood sugar levels, blood pressure, and protein, bone, and DNA production.

If a person is found to be deficient in magnesium, magnesium is the best way to naturally. Magnesium, which is naturally absorbed from food, is not harmful and is excreted in the urine, even when consumed in large quantities.

Magnesium is also available in various forms, including multivitamin minerals and other dietary supplements. These supplements can help those who suffer from a deficiency. One of the commonly used supplements is magnesium glycinate.

Magnesium glycinate use

magnesium glycinate preparation

Magnesium glycinate is often used because it is the best-absorbed form of magnesium, one of the least harmful to the stomach.

Unlike other magnesium forms, it does not cause as many side effects, such as gastrointestinal disorders or loose stools. This property makes magnesium glycinate a good supplement for patients who have undergone bariatric surgery.

People who have kidney problems should consult a doctor before taking magnesium glycinate. If too much magnesium is consumed, there can be problems with excess excretion.

Advantages of magnesium glycinate

Some people benefit more from magnesium glycinate than others, which may positively affect their health. This includes people with the following problems:

High blood pressure or heart disease: Magnesium supplements can help reduce blood pressure in small amounts.

Type 2 diabetes: People with more magnesium in their diet can really reduce their risk of developing type 2 diabetes. Magnesium helps break down sugar and can reduce the risk of insulin resistance.

Osteoporosis: Magnesium plays an important role in developing healthy bones, and people with higher levels of magnesium may have higher bone mineral density. This is important in reducing the risk of bone fractures and osteoporosis.

Migraine headaches: People who experience migraine headaches sometimes have low magnesium levels in their blood and other tissues. Supplements can help reduce the incidence of migraines.

Depression: Inadequate magnesium levels reduce serotonin levels, and antidepressants have increased magnesium levels in the brain.

Measuring magnesium levels is not easy because magnesium is found inside cells or bones instead of in the bloodstream. Blood tests may give incorrect results.

Doctors usually measure the serum concentration of magnesium in the blood, saliva, or urine to make the best decision.

It is important to allow the doctor to make a final diagnosis because the symptoms usually associated with the deficiency may be related to another health problem.

Sources of magnesium

Magnesium is found naturally in foods that are consumed daily. Most people can get the recommended daily dose by adding foods rich in magnesium to their daily diet. Foods that contain magnesium:

Vegetables, nuts, seeds
Whole grains
Spinach and other herbaceous vegetables
Enriched breakfast cereals and other fortified foods
Milk, yogurt, and other dairy products

Magnesium glycinate The plugin is available for online purchase. Consult your doctor before taking supplements.

Daily doses

The recommended daily amount of magnesium depends on the age and sex of the person. The National Institutes of Health provides guidelines for the daily recommended amount in milligrams (mg).

Age – The recommended amount
Children 7 – 12 months 75 mg
Children 1 – 3 years 80 mg
Children 4 – 8 years 130 mg
Children 9 – 13 years 240 mg
Teenagers boys 14 – 18 years 410 mg
Teen girls 14 – 18 years 360 mg
Men 400 – 420 mg
Women 310 – 320 mg
Pregnant teenage girls 400 mg
Pregnant women 350-360 mg
Teenagers breastfeeding 360 mg
Breastfeeding women 310-320 mg

Magnesium deficiency

magnesium deficiency problems

Risks and complications

Only doctors should diagnose magnesium deficiency. They can perform blood tests and identify an accurate plan of action to return the magnesium level to the right value.

High amounts of dietary magnesium supplements, including magnesium glycinate, can cause side effects such as diarrhea, nausea, and stomach cramps. Extremely high magnesium intake can lead to irregular heartbeat and cardiac arrest, which can be dangerous.

Magnesium glycinate and other supplements may also interfere with or interact with some medications. Among them are:

Bisphosphonates are used to treat osteoporosis. The body does not absorb these drugs well if taken immediately after taking supplements or drugs containing a high amount of magnesium.

Antibiotics. They will not be well absorbed by the body if taken too soon before or after the addition of magnesium.

Diuretics may increase or decrease the loss of magnesium in the urine.

Prescription drugs used for treating gastroesophageal reflux or peptic ulcers can lead to low blood magnesium levels when taken for extended periods of time.

Exceptionally high doses of zinc in the form of supplements can interfere with the absorption and regulation of magnesium in the body.

Zinc picolinate as an enhancer of immunity and a fighter against chronic diseases

Zinc is a mineral that the body uses to perform several functions. There are many dietary forms of zinc, and one of them is zinc picolinate. It is also the primary component of the body’s metabolism. Zinc serves as a substrate in many biochemical processes within the body, and a lack of zinc in the diet can lead to disruption of these functions.

Picolinic acid occurs naturally in our body and acts as a chelator. It is the most efficient chelator for metals such as chromium, zinc, manganese, copper, iron, and probably molybdenum. Picolinic acid is formed from tryptophan, an amino acid. Picolinic acid is produced in the liver and then leads to the pancreas. During digestion, it is part of the secretion mixed with ingested food to facilitate these minerals’ absorption.

When zinc is chelated with picolinate amino acids, our body forms zinc picolinate.

Absorption of zinc picolinate

The absorption of zinc in the body is a complex process that involves passing through intestinal membranes, bloodstream, and individual cells. Zinc picolinate is a well-absorbed form of zinc in the body. Compared with zinc citrate and zinc gluconate, which are known to be useful and chelated forms of zinc. All three were tested relative to each other for human use, and zinc absorption was improved when combined with picolinic acid.

What are the functions of zinc in the body?

The body uses zinc to perform many biochemical processes. The body uses zinc to perform various enzymatic functions, especially catalytic in nature. It has also been found to impact the immune system, protein synthesis, wound healing, DNA synthesis, and cell division.

During pregnancy, childhood, and adolescence, zinc has been found to support normal growth and development. It has also been found to allow the senses of taste and smell to function properly.

Advantages of zinc picolinate

  • It acts as a general booster of immunity
  • Enhances neurotrophic factor of brain origin
  • Improves learning and memory
  • Fight against colds
  • Helps heal wounds
  • It reduces depression
  • It helps control acne problems
  • Helps expose lead
  • Provides the required amounts of zinc
  • Reduces the risk of prostate cancer
  • It helps prevent and treat liver disease and cirrhosis.
  • Reduces the risk of chronic diseases associated with aging
  • It helps prevent age-related macular degeneration.
  • It improves fertility in men.
  • Shortens the duration of diarrhea

Functions of zinc picolinate as a general enhancer of immunity

immune system
Immune system

Zinc picolinate serves as an immune booster because it strengthens molecules that can fight diseases, such as tumor alpha necrosis factor or TNF. This is possible because zinc affects the level of leptin (a key factor in the regulation of energy needs, appetite, and metabolism) within the body’s circulation, increasing TNF production.

Zinc is known to play a central role in the human immune system. People who lack zinc at the appropriate body levels can easily become prey to various pathogens that cause diseases. Zinc mediates several functions within the immune system, such as lymphocytes and macrophages, through its myriad roles in cellular activities such as DNA replication, RNA transcription, and cell activation.

Zinc picolinate enhances levels of brain-derived neurotrophic factor (BDNF) in the body

Studies show that zinc picolinate can increase the level of BDNF in the body. Zinc supplementation improved the mood of the subjects. BDNF levels are also associated with good brain development leading to better memory and learning.

Zinc picolinate improves learning and memory

memory and the influence of zinc

According to a study he did at the University of Toronto, which was published in the journal Neuron, zinc can play a key role in how neurons communicate and communicate with each other. This implies how memory is formed and the process by which we learn.

Zinc picolinate helps treat colds

Zinc-containing tablets can shorten the duration of a cold by as much as 40 percent, according to a study published in The Open Respiratory Medicine Journal from 2011 years. The conclusion is that the shorter course of the common cold was due to large amounts of zinc.

Another study, published in The Cochrane Review of Systematic Reviews, shows that zinc taken either in the form of syrup or tablet shows advantages when it comes to the shorter duration and severity of colds in healthy people taken within 24 hours of the onset of symptoms.

Zinc Picolinate helps in wound healing

Zinc helps maintain the integrity and structure of the skin. It has been observed that people suffering from metabolic disorders caused by zinc deficiency or people with low zinc levels for any reason often experienced the appearance of chronic wounds and ulcers on the skin. Many medications for diaper rash and other skin irritations list zinc as a primary component or supplement.

One study showed that zinc could improve re-epithelialization, reduce inflammation, and reduce bacteria’s development, which can improve ulceration on the legs. Topical application of zinc agents to wounds can reduce zinc deficiency within the affected area and produce pharmacological effects.

Zinc picolinate helps reduce depression

depression and axiosity

The presence of zinc picolinate reduces the symptoms of depression through the interaction of BDNF with serotonin in certain parts of the body. In a previous study, the symptoms of depression in obese subjects were reduced, which leads to an overall improvement in mood.

With the use of SSRI antidepressants (selective serotonin reuptake inhibitors), the addition of zinc has shown better results in improving major depressive disorders compared with treatment using SSRI given with placebo.

Zinc picolinate helps control acne problems

Zinc is thought to act directly on redness and swelling caused by acne by acting on the microbiological inflammatory balance. When used in combination with an antibiotic, zinc can facilitate antibiotics’ absorption.

Zinc picolinate helps with lead exposure

In lead toxicity experiments, zinc and thiamine, alone or in combination, have been shown to be effective in reducing the accumulation of lead in the blood, liver and kidneys.

Provides the need for zinc, especially for pregnant women

gynecologist during pregnancy

Zinc supplementation is recommended for growth and development during pregnancy, childhood, and adolescence. There is a physiological drop in zinc levels during pregnancy, so pregnant women are prescribed supplements to prevent any complications due to reduced zinc levels within the body. It also provides support for the child’s development.

It reduces the risk of developing advanced prostate cancer

Studies have shown that long-term supplemental zinc intake may reduce the risk of developing clinically relevant advanced disease. No evidence has been found that additional zinc could reduce the risk of prostate cancer, but it does reduce the risk of developing regional invasive or metastatic prostate cancer.

There is growing evidence to support claims that zinc plays an integral role in keeping the prostate healthy. Zinc appears to help prevent prostate tumor growth. Zinc creates an environment that seems toxic to cancer cells inside the prostate, thus preventing malignancy development.

The risk of developing advanced prostate cancer showed a reduction of 60 percent when there was an intake of more than 15 mg of zinc. Higher dietary zinc intake is also associated with a reduced risk of dying from prostate cancer and increased protection among localized prostate tumors.

Zinc picolinate helps prevent and treat liver disease and cirrhosis

Zinc levels in humans reduce liver disease development ease, and studies show that supplementation can restore zinc deficiency’s clinical signs. Zinc supplementation can also improve liver function in certain diseases.

Reduce the risk of chronic diseases associated with aging with zinc picolinate

You can avoid inflammatory diseases by improving zinc intake. A study from the University of Oregon found that you can reduce the risk of inflammatory diseases by increasing zinc intake through diet and supplements. For decades, we have known that zinc plays a significant role in keeping the immune system functioning optimally and that a lack of this essential element can lead to increased inflammation in chronic diseases and can lead to new inflammatory processes.

Zinc picolinate helps prevent age-related macular degeneration (AMD)

A study published in the Archives of Ophthalmology indicates that zinc prevents retinal degradation by preventing cell damage. This stops the progression of age-related macular degeneration (AMD), a condition that leads to vision loss.

Zinc has been shown to improve fertility in men

Low sperm quality is associated with low levels of zinc in the body. One study conducted in the Netherlands found that subjects who used zinc sulfate and folic acid supplements increased sperm in the sample. Another study concluded that low zinc intake could lead to poor sperm quality and male infertility.

Zinc can also increase testosterone levels. A study involving elite wrestlers who took zinc supplements for four weeks with their regular diet found that they had significantly higher levels of total and free testosterone after rest and strenuous training compared to the period before taking the supplements. The results suggest that zinc supplementation may prevent the inhibition of testosterone levels.

People who do not do extreme sports can benefit from increased zinc intake and supplementation. In a study conducted among men aged 20 to 80, those who restricted zinc intake had a significant drop in testosterone levels. In contrast, those who took zinc supplements (older people with marginally reduced zinc levels) had increased testosterone levels, leading to conclude that zinc plays an important role in testosterone levels among average men.

Due to the possibility of zinc affecting testosterone levels, you also considered its role in sexual health and libido. When testosterone levels increase, sexual health and sex drive improve. Zinc can reduce erectile dysfunction, which is a secondary consequence of low testosterone levels.

In patients with kidney disease, who experience sexual dysfunction, it has been found that the use of zinc supplements increases testosterone levels and improves the potency and frequency of sexual intercourse.

Zinc picolinate shortens the duration of infectious diarrhea

It has been established that zinc supplementation among patients with infectious diarrhea leads to a faster recovery time from the disease. In addition to shortening the disease’s duration, it has been determined that zinc supplementation also reduces the severity of the disease.

A recent study aimed at increasing the use of zinc to treat diarrhea in children found that taking pills for 10 days effectively solved the problem of diarrhea and that this supplement can help prevent the recurrence of the disease.

How to ingest zinc picolinate

The human body does not have a specialized storage system, so a daily intake is recommended to meet the body’s needs. Zinc can be combined with iron when hematological problems are solved. You can also combine it with vitamin C or any multivitamin. In most cases, zinc is a component of any multivitamin formulation on the market.

You should maintain sufficient zinc to increase the potential of zinc or enhance the desired effects. Combined preparations that complement you can use zinc functions, or those that can create a synergistic effect, which increases the activity of zinc, or vice versa, or preferably both.

How zinc picolinate is prepared and taken (correct dose)

The levels of recommended daily values (RDA) and levels of adequate intake (AI) are indicated here. Recommended daily values are based on scientific research evidence, while levels of adequate intake are determined by the authorities when there is insufficient evidence to develop an RDA.

For babies (AI)

0 to 6 months: 2 milligrams daily (mg/day)

7 to 12 months: 3 milligrams daily (mg/day)

For children (RDA)

7 to 12 months: 3 milligrams daily (mg/day)

1 to 3 years: 3 milligrams daily (mg/day)

4 to 8 years: 5 milligrams daily (mg/day)

9 to 13 years: 8 milligrams daily (mg/day)

For adolescents and adults (RDA)

Men 14 years and older: 11 milligrams daily (mg/day)

Women 14 to 18 years of age: 9 milligrams daily (mg/day)

Women 19 years of age and older: 8 milligrams per day (mg/day)

Pregnant women, aged 19 and over: 11 milligrams per day (mg/day)

Lactating women, 19 years and older: 12 milligrams daily (mg/day)

Red meat and poultry provide most of the required zinc values in the average diet. you can also obtain zinc from beans, nuts, whole grains, and dairy products.

Side effects of zinc picolinate

Oral forms of zinc intake are largely safe; however, they can block the absorption of copper, leading to the development of anemia.

Taking high amounts of zinc is unsafe. High doses that exceed the recommended permitted values can cause the following adverse effects:

– Fever

– Cough

– Nausea

– Decreased number of white blood cells

– Vomiting / Feeling nauseous

– Stomach pain

– Headache

– Fatigue

Poor digestion

– Diarrhea

Care should be taken when taking zinc supplements because overdoses can lead to a decrease in the absorption of copper, which also plays a vital role in the body.

Besides, it is suspected that increased zinc levels can lead to kidney stones. Additional research is being conducted in this field.

Zinc deficiency and precautions

Zinc deficiency is usually a consequence of insufficient dietary intake. In some cases, it can be a consequence of malabsorption and chronic diseases. Some of the signs and symptoms of zinc deficiency are:

– Loss of appetite

Anemia

– Slow wound healing

– Skin condition

– Abnormal taste and smell

– Depression

– Diarrhea

– Hair loss

– Difficult or prolonged labor in pregnant women

How and where to buy zinc picolinate

Zinc picolinate is available at local grocery and health food stores. It may not be the usual form of zinc on the market. Still, it is known to be the most available and useful due to its effects of strengthening immunity and improving the organism’s condition. Reliable online sellers also offer zinc picolinate from reliable manufacturers. If you cannot buy zinc supplements from local suppliers or at the local market or pharmacies, you can contact online stores.

Summary (Most important details about zinc picolinate)

  • Zinc picolinate is an essential mineral that is needed for good health. Adequate amounts of zinc should be consumed from a balanced diet and/or supplementation to reap the health benefits zinc offers.
  • Zinc is a substrate in many biochemical processes within the body that results in many benefits that include: improved immunity, improved brain function – including memory and learning, shortens cold durations, improves wound healing, improves mood and fights depression, helps control acne, helps in the management of lead toxicity, prevents the development of prostate tumors, prevents liver disease and cirrhosis, prevents the development of chronic diseases associated with aging, improves male sexual function and shortens the duration of the disease in patients with diarrhea.
  • You can purchase zinc at any pharmacy within the local market. You can also purchase it through trusted online retailers.

MSM powder – 8 scientifically supported benefits

Methylsulfonylmethane MSM powder or MSM tablets, commonly known only as MSM, is a popular dietary supplement used to treat various symptoms and conditions.

It is a natural compound that contains sulfur and can be found in plants, animals, and humans. It can also be produced in the laboratory to create dietary supplements in powders or capsules.

MSM is widely used in natural medicine and by people looking for a natural way to relieve joint pain, reduce inflammation, and increase immunity.

Besides, research supports its use in treating several conditions, from arthritis to rosacea (redness of the face).

Here are 8 health benefits of MSM.

MSM powder can reduce joint pain, which could improve mercury quality

knee pain

One of the most popular uses of MSM is to reduce joint pain and muscles.

MSM powder is beneficial for those suffering from joint degeneration,  common causes of pain in the knees, back, arms, and hips.

Joint degeneration can negatively affect life quality by limiting your movements and mobility itself.

Studies have shown that MSM significantly reduces inflammation in your body. It also prevents the breakdown of cartilage, a flexible tissue that protects the ends of the bones in the joints.

A study of 100 people over the age of 50 found that treatment with a supplement containing 1,200 mg of MSM for 12 weeks reduced pain, stiffness, and swelling in the joints, compared to placebo.

The group receiving the supplement also reported improved overall quality of life and less difficulty walking in and out of bed.

Another study in 32 people with lower back pain found that taking a glucosamine supplement containing MSM significantly reduced lumbar stiffness and pain when moving, plus a significantly increased quality of life.

Studies have shown that MSM is effective in reducing joint pain, stiffness and swelling. This can improve your quality of life.

It has anti-inflammatory effects, such as increased levels of glutathione

The anti-inflammatory properties of MSM have been well documented by scientific research.

MSM is believed to inhibit the NF-κB protein involved in your body’s inflammatory reactions.

It also reduces cytokine production, such as tumor necrosis factor-alpha (TNF-a) and interleukin 6 (IL-6), signaling proteins associated with systemic inflammation.

Aside from this, MSM powder can increase glutathione, a powerful antioxidant produced by the human body.

For example, taking MSM supplements significantly reduces inflammation in mice that have stomach ulcers by preventing the release of inflammatory cytokines, including TNF-α and IL-6, and increasing glutathione levels.

Another study involving 40 physically active men showed that taking 3 grams of MSM before an exhausting exercise reduces the release of inflammatory cytokines and prevents excessive stress of immune cells compared to placebo.

MSM can reduce the release of inflammation-related molecules, such as TNF-α and IL-6, as well as the strength levels of strong antioxidant glutathione.

It can speed up recovery after exercise by reducing muscle damage and stress

During exhaustive exercise muscle, damage and oxidative stress occur.

This leads to the fact that athletes often have inflammation and muscle pain problems, which can negatively affect their sports performance and interfere with training.

MSM can naturally speed up muscle recovery after intense exercise by reducing inflammation and oxidative stress.

A study in 18 men showed that taking 50 mg of MSM powder per kilogram of body weight for 10 days significantly reduced exercise-induced muscle damage and increased antioxidant activity after running 14 km.

It can also be useful for reducing pain after prolonged exercise.

In one study, 22 healthy women received 3 grams of MSM or placenta daily for three weeks, which led them to endure a half marathon. The group receiving MSM reported less muscle numbness and joint pain than the group receiving placebo.

Another study showed that male athletes who took 3 grams of MSM powder daily for two weeks had lower levels of IL-6 and less muscle pain after intense training.

MSM powder can help reduce pain, muscle damage and oxidative stress after intense exercise, which helps you recover faster.

MSM helps alleviate the symptoms of arthritis by reducing pain and stiffness

Arthritis is a common inflammatory condition that causes pain, stiffness, and reduced motion in the joints.

Because MSM has powerful anti-inflammatory properties, it is often used as a natural alternative to medications to improve arthritis-related symptoms.

A study in 49 people with osteoarthritis of the knee showed that taking 3.4 grams of MSM a day for 12 weeks reduced pain and stiffness and improved physical function compared to placebo.

Besides, it may increase the effectiveness of other common supplements used to treat arthritis, such as glucosamine sulfate, chondroitin sulfate, and boswellic acid.

One study found that combining MSM with glucosamine and chondroitin was more effective in reducing pain and stiffness in people with osteoarthritis knees than glucosamine and chondroitin alone.

Another study showed that taking 5 grams of MSM and 7 grams of boswellic acid daily was more effective than glucosamine in reducing pain and improving function in people with osteoarthritis of the knee.

Moreover, people who took MSM and boswellic acid as supplements were less dependent on anti-inflammatory drugs than those receiving glucosamine.

MSM supplements have been shown to help  in reducing pain and stiffness in people with arthritis. They can also help improve physical function.

It can help alleviate allergy symptoms by reducing inflammation

allergy and hpv virus

An allergic rhinitis allergic reaction causes symptoms such as watery eyes, sneezing, itching, runny nose, and nasal congestion.

Common triggers of allergic rhinitis include allergens of animal origin, pollen, and mold.

After exposure to the allergen, many inflammatory substances such as prostaglandins and cytokines are released, which leads to unpleasant symptoms.

Studies have shown that MSM powder can reduce the symptoms of allergic rhinitis.

It can reduce allergic reactions by reducing inflammation and inhibiting cytokines and prostaglandins’ release.

A study in 50 people with allergic rhinitis found that a dose of 2,600 mg of MSM a day for 30 days reduced symptoms, including itching, congestion, shortness of breath, sneezing, and coughing.

Besides, participants noted a significant increase in energy up to 14—days of use.

MSM can help reduce allergy-related symptoms – including coughing, shortness of breath, congestion, sneezing and fatigue – by reducing inflammation.

It can improve immunity and help you stay healthy

immune system and msm powder
Immune system cells

The human immune system is a specialized network of tissues, cells, and organs that protect the body from diseases and illnesses.

He may be weakened by stress, illness, poor diet, lack of sleep, or lack of activity.

Sulfur compounds such as MSM play an important role in the immune system’s health.

For example, MSM can reduce oxidative stress and inflammation that can weaken immunity. Because it effectively reduces the levels of inflammatory compounds such as IL-6 and TNF-a, MSM powder can reduce the stress of the human immune system.

Besides, it plays an important role in creating glutathione, the main antioxidant of the human body. It can also help increase the levels of this important composition.

Having adequate glutathione levels is crucial for the overall health and function of the human immune system.

Research has shown that MSM effectively restores glutathione levels and reduces inflammatory markers in muscle cells that HIV proteins have weakened.

MSM can help strengthen the immune system by reducing inflammation and increasing glutathione levels.

It can improve skin health by strengthening keratin

Keratin is a protein that acts as the main structural component in hair, skin, and nails.

It contains high levels of cysteine, an amino acid that contains sulfur. That is why inflamed hair leaves a characteristic sulfur smell.

MSM can be beneficial for skin health by acting as a sulfur keratin donor. This, in turn, can help strengthen this important protein.

MSM also helps reduce inflammation, which can damage skin cells and cause signs of premature aging, such as wrinkles.

It can even reduce the symptoms of problematic skin conditions, such as rosacea, which can cause redness, irritation, and skin inflammation.

One study showed that, when applied to the skin, MSM significantly reduces redness, itching, inflammation, hydrates the skin, and restores its color in people suffering from skin redness.

MSM can improve skin health by strengthening keratin and reducing inflammation. It can even help reduce the symptoms of certain skin conditions.

MSM may have anti-cancer properties

One of the most recent research areas involving MSM is studying its effectiveness in fighting cancer cells. Although research is limited, the results so far are promising.

Several studies have shown that MSM powder inhibits cancer cells’ growth in the stomach, esophagus, liver, colon, skin, and bladder cancer.

It seems to do this by damaging the DNA of cancer cells and stimulating cancer cells’ death.

MSM appears to prevent the spread of cancer cells, also known as metastasis.

A study in mice with liver cancer showed that those injected with MSM had a smaller tumor, fewer tumors, and less liver damage than those who did not receive this treatment.

Another study in mice showed that MSM inhibited breast cancer cells’ growth.

Although these results are encouraging, further research is needed to determine MSM’s safety and efficacy in cancer treatment.

Research has shown that MSM shows cancer-fighting properties in laboratory tests and tests performed on animals, but more research is needed.

MSM safety and side effects

MSM is considered safe and is generally well tolerated with minimal side effects.

Larger regulatory agencies, such as the FDA – the US Food and Drug Administration, have assigned the MSM the GRAS label, which indicates that safe to use.

Numerous toxicity studies have been done to assess the safety of MSM, and doses up to 4,845.6 mg per day (4.8 grams) appear to be safe.

However, some people may experience mild reactions if they are sensitive to MSM powder and MSM tablets, such as stomach problems such as nausea, bloating, and diarrhea. When applied to the skin, it may cause mild skin or eye irritation.

Also, there are concerns about mixing MSM with alcohol because other drugs that contain sulfur can cause side effects when mixed with alcoholic beverages.

However, studies have not investigated this potentially problematic combination.

The MSM supplement is generally considered safe. However, in some people it can cause side effects such as nausea, diarrhea and skin reactions.

Relationship between MSM and selenium

Selenium is a trace element that helps defend against pathogens. It also protects against harmful free radicals and is an important substance for the walls of blood vessels, eyes, and connective tissue.

Selenium brings to the site of using an amino acid that contains the sulfur methionine. When the body lacks sulfur, methionine is also absent. Consequently, selenium can no longer be transported and no longer reaches its application areas. Selenium deficiency affects the body’s defense system and makes people susceptible to inflammation and infections. If the important substance MSM is missing, many body functions are impaired.

How is MSM made?

Commercially available MSM is produced synthetically in several chemical reactions. The starting materials for MSM are substances DMSO (dimethyl sulfoxide), a by-product of paper production, and hydrogen peroxide. The reaction of both substances leads to the crystallization of MSM. A process used worldwide to produce versatile MSM.

Although wood and other plants contain MSM, it is uneconomical to extract MSM from plants because the concentration in plant fibers is too low. The MSM obtained from it is often highly contaminated and may not contain GMOs (without genetic engineering). Complex distillation and filtration at high temperatures are necessary, making the production of MSM in large quantities environmentally and economically unprofitable. Therefore, the production of MSM from these natural resources is not suitable.

MSM is also a substance found in fresh raw foods such as meat, vegetables, grains, fruits, coffee, and cow’s milk. However, organic sulfur is destroyed by cooking or industrial processing. The result is a noticeable lack of sulfur in our bodies. Therefore, MSM is becoming increasingly important as a dietary supplement.

Who should not take MSM?

Daily dietary supplements with MSM are generally safe and without side effects. If you start with MSM, you should start with small doses and slowly increase your intake every week. It can be taken up to 5 grams a day after about four weeks. Either once a day or in two or three units a day before meals. This is not a problem if you overdose because excess MSM can be easily excreted in the urine and stool.

Conclusion

MSM is a popular supplement with a wide range of uses.

Research shows that it can help reduce joint pain, reduce inflammation, improve skin health, reduce allergy symptoms, and speed up recovery after exercise.

Besides, some evidence suggests that MSM powder may improve the immune system and may have anti-cancer properties.

MSM seems to be safe, and research indicates minimal side effects.

Although the current MSM research results are promising, further research is needed to understand all of its potential benefits and possible side effects.

The price of MSM powder is very affordable and can be found in many larger pharmacies and health food stores.