Mastic is a viscous fragrant substance.  The Latin name of this plant is Pistacia Lentiscious and it is a plant that has long been growing in the southern part of the island of Xios, which is located in the Aegean Sea. Pentachio Lentiscious wood  It is considered a medicinal plant and is used as a very powerful preparation for healing. It is known for its healing properties in all countries that access the Mediterranean Sea. 

It is used to treat a number of conditions and diseases such as gastritis and indigestion. Scientists have confirmed many positive properties of mastic rubber in previous research. In laboratory research and experiments, scientists have confirmed the useful elements of Pistacia Lentiscious  as natural resins for the treatment of many diseases.

Mastic as therapeutic agents

mastic therapeutic agent

Mastic has a wide role in various therapeutic methods and is used as septicitis, it is associated with use during surgical interventions, it cures ulcers and various forms of malignancy.  The research confirmed its use as an antioxidant and pesticide, and also expressed its effect on reducing high cholesterol, the effect on chronic disease, diabetes and hypertension. Its therapeutic value also lies in its influence on various  lines of harmful microbes including very dangerous Helicobacter pylori .

This offensive microbe is the cause of gastritis and ulcers on the duodenum. Helicobacter pylori or the Latin name Helicobacter pylori is a very important link in the development of gastric malignancy. Elimination of H. pylori bacteria from the gastrointestinal tract affects the secondary inhibition of gastric and intestinal malignancy, the development of which is stimulated by this bacterium.

Mastic research

Modern research has been conducted in Greece and  in Florida  USA by two expert teams on colon malignancies. Their intention was to understand how Mastic kills colon cancer cells, and they conducted their research in laboratory conditions. It has been established that Mastic has a different effect on carcinogenic diseases and that its effect depends on the amount that is taken into the body.

The larger the amount and the stronger the intensity of the action, the stronger the effect of the action on the cancer will automatically be. When the exposure was for 48 hours with a mastic strength of 25 micrograms per milliliter, the malignant cells remained attached to the extracellular membrane, but already when the mastic strength was increased to 50 micrograms per milliliter, about 50% of the cancer cells were removed from the membrane. and when the concentration of mastic introduced into the body was 100 micrograms per milliliter, 100% of the malignant cells were removed from the sample.

Mastic and cancer

In the last few years, there has been an increasing concentration of positive influences of Mastic and cases of destruction of various types of human malignancies. Mastic or resin from Mastic belongs to any group of Tritepenoids which are especially responsible for its anticancer properties.  Mastic can be as effective as some anti-neoplastic compounds thanks to these compounds.

A significant number of researches have marked malignant diseases that are affected by Mastic, and over time, this list is expanding. Malignancy of the prostate, colon,  rectum, leukemia and lung malignancy are diseases on which mastic has an anticancer effect.

Research with cancer

chewing gum mastic

In 2005, a scientific team led by Dr. Balan discovered that a mixture of hydrocarbon and mastic fluids promotes apoptosis in HCT116 cancer cells of human colon cancer.

In this study, Balan et al. Confirmed that a solution of ethanol and mastic  interfere with the spread and growth of HCT116 human colon cancer. It was found that a concentration of 200 milligrams per kilogram per day for 4 days (divided into three daily doses) reduced tumor development by 35% and the effects of this treatment were determined with an effect that was activated 35 days later. Scientists have proven that Mastic has an anti-malignant effect on colon cancer.

In short, studies have found that Gum Mastic has a very effective action against malignant activities such as several types of human neoplasia, prostate, colon, lung, pancreas and hematological malignancies. This is published in the latest  report of the section for forensic medicine and toxicology, Faculty of Medicine, University of Athens .

Today’s statistics on the antitumor activities of mastic and its composites are presented below and the results are derived from the same. In this report, the scientists focused on the molecular processes that affect the direct and indirect influences associated with malignancy. Components that have their place in the chemical class of Triterpendoids are compounds that play the largest role in the antimalignant actions of mastic.

Influence of mastic and its ingredients on cancer

The influence of mastic and its ingredients are:

1. Nuclear factor kappa-Beta: a protein composite that regulates the copy of deoxyribonucleic acid. Inadequate regulation of the kappa-Beta nuclear factor leads to the development of malignancy.

2. Mastering the JAK-STAT pathway – this pathway is very important in the development of cancer cells.

3. Inhibition of vascular endothelial growth factor –  increases the development of blood vessels. Mixing the amount of new blood vessels reduces the influx of nutrients and the development of tumors.

4. Reduction of glutathione

We can conclude that mastic is a very successful anticancer agent that can play a very important role in combination therapies with other anticancer drugs, and in the near future we should expect new information from the latest medical tests. One thing we can conclude for now, this preparation, which has been used in traditional medicine for many years, has been given a chance again through the discovery of its influence in the treatment of cancerous diseases.

Mastic for pharmaceutical purposes

Modern studies have shown that mastic and mastic oil have anti-inflammatory properties. This is due to the oleanolic acid that the mastic contains. This resin has a healing and anti-inflammatory effect. Mastic is used to treat numerous disorders, such as inflammation of the dental system, feeding system, gastric mucosa, etc. It also helps against stomach ulcers and hemorrhoids .

Its stimulating and revitalizing effect prevents unpleasant reactions of the body, such as indigestion and gas. It has an antioxidant effect and thus protects the whole organism and the digestive system.

According to recent studies University of Nottingham , published in The New England Journal of Medicine, antimicrobial properties of mastic can fight bacteria Helicobacter pylori . Even small amounts of mastic (1g / day) for two weeks can cure an ulcer on the gastrointestinal tract in a short time.

Mastic also lowers blood cholesterol levels.

It also has a significant effect on liver function by having detoxifying activity. It helps break down cholesterol and thus reduces the risk of heart disease .

Mastic also works against certain viruses.

Mastic has a very specific property of mastic that can hardly be found in any other medicine.

According to scientific studies, its active ingredients also help in the treatment of herpes simplex. Herpes is an infection of the skin that manifests itself on the skin, around the lips and genitals.

Areas of application of mastic

Mastic is used in the fields of lithography, painting, brewing, textiles, and cotton production.

Perfume making

Mastic oil is used both as a perfume and as a perfume stabilizer.

Mastic oil is also used in the production of cosmetics and perfumes (creams, body lotions, shampoos).


Mastic oil has valuable properties from which beauty can benefit. Face creams with mastic ensure firm and clean skin. It is also used successfully in hand creams, body lotions, shower gels and soaps.

Cooking mastic

Mastic is used as a spice that gives many recipes a pleasant and unmistakable aroma. Mastic is also an important dietary supplement, especially when it lacks trace elements. Lebanon or Syria produces a traditional type of cheese with mastic and mastic flavor.

The aroma of mastic is highly valued in Arabic cuisine and bakery. Mastic also gives bread a special taste.

Mastic in the bakery

With its fine aroma, you can enrich sweets such as Lokume, yeast braids and Greek New Year’s cakes (recipes from Asia Minor).


Mastic is widely used to make liqueurs and ointments. Liqueurs and ouzo, which get a fine aroma from mastic, are very famous. It is also stated that mastic drinks have the property adapted to the stomach and its optimal work.