Dimethyl sulfoxide, DMSO, is rightly called a “miracle drug,” not because of pervasive marketing efforts but based on testimonies from people who have confirmed the great benefits of this chemical. The history of his nature and finding his way to the medical application is a story that anyone should really share with other people.
As a product, it was first identified in the wood industry in 1867. years by a Russian scientist, Alexander Zaitsev. Since 1953. Its industrial use has continued to increase mainly for raw quality solvents. Since then, approximately 40,000 articles on DMSO chemistry have appeared in many scientific journals.
Dimethyl sulfoxide is a colorless liquid that is said to smell like garlic. Its appearance in medicine began with the role of a “preservative” for organ transplantation. 1961. A doctor named Stanley Jacob MD, a former head of the organ transplant department at the University of Health Studies in Oregon, Portland noticed that DMSO manifests some unique characteristics.
Human skin absorbed it very well. Driven by curiosity about its impact on human health, he discovered that this chemical performs medical miracles. DMSO has relieved pain, reduced inflammation, and improved treatment in many medical conditions. The stories of many people about the effect of this medicine and its media distribution have led to a great acceptance of this substance, which has attracted attention around the world regarding its medical use.
So far, about 11,000 articles have been published on the healing properties of DMSO. Until now, no serious side effects, except allergic ones, have been reported, and this chemical has only received even greater support.
What cures DMSO?
DMSO is like aspirin in the medical world. DMSO cures headaches, reduces fever, relieves pain, and protects the cardiovascular system from the destructive effects of thromboembolic complications. DMSO is also easily absorbed by human skin, passes through membranes, and shows analgesic activity. The announcement about its analgesic action is almost instantaneous.
It relieves the patient of pain almost at the same time. Not only does it reduce pain, but DMSO also reduces inflammation. 1978. In Cleveland, Ohio, at the Cleveland Clinical Foundation, 213 patients with inflamed genitourinary disorders received DMSO, and most found significant relief.
Studies obtained the same results in patients with rheumatoid arthritis and osteoarthritis. If there are any side effects, it is only the smell of garlic.
Its medical use is not stopped as just an analgesic, anti-inflammatory. Still, it has been expanded and will continue to be in the future, on its accelerated healing power of the central nervous system.
DMSO has shown consistent results in lowering intracranial pressure, stabilizing blood pressure, increasing blood flow to the injured part, promoting an increased healing rate. Its use has been extended to stroke patients, for whom DMSO helps with clot-dissolving activity. Patients who had a heart attack and patients with diseases of the central nervous system, and taking DMSO, received improved treatment and early rehabilitation.
and Research with DMSO
Studies continue to provide insight into the mechanism of action of DMSO. It penetrates the skin and cells very easily and is quickly distributed in the body through the blood.
Laboratory studies indicate that the analgesic effect of DMSO mediates through its effect on blocking peripheral C proteins, which are responsible for transmitting painful signals. The effect is almost instantaneous. Research also continues to prove the anti-inflammatory effect of DMSO consistently. It has a similar effect in all types of inflammatory conditions that are not related to the tumor or infection.
DMSO also helps increase blood flow to the affected area and accelerates tissue recovery. DMSO’s proven antioxidant effect leads many researchers to investigate its effect in cancer treatment, defending healthy cells from free radicals.
DMSO and radiation
About 40 years ago, studies were performed on mices that showed the radioprotective effect of DMSO. Benjamin Hyman’s study, published in 1967. year, including X-irradiated mice previously treated with DMSO, stimulated interest in the radioprotective effect of DMSO.
It is well known in science that nuclear radiation damages cell directly or indirectly through the formation of free radicals that damage cell DNA. With the media’s help, most people today are familiar with the carcinogenic effects of high-energy radiation such as nuclear radiation.
The recent disaster with Fukushima Central reminded the world, once again, of the dangers of nuclear radiation. This brings great trouble, especially to the Japanese affected by this catastrophe, which reawakened the nightmares of Hiroshima and Nagasaki. They have lived in paranoia ever since the disaster happened. As nuclear radiation may not be symptomatic, but it definitely does damage, people know they are at high risk of cancer in the future. They were looking for a substance that protects against radiation, supported by scientific findings. The DMSO has proven to be an up-and-coming candidate.
Dimethylsulfoxide has long been used as a free radical scavenger due to its specific reactivity with hydroxyl radicals. Studies show that the radioprotective effect of Dimethylsulfoxide, DMSO, is mediated by the suppression of hydroxyl (-OH) radicals that are usually caused by ionizing radiation. Previous studies have included DNA exposure to ionizing radiation treated with a high DMSO concentration. The result showed a significant reduction in DNA strand burst. The result, however, was far from clinical application, given that the experiment was performed at a high concentration of DMSO, which was toxic.
Further studies were performed on the radioprotective effect of DMSO at the therapeutic level. Genro Kashino and a group of Japanese researchers recently published a journal related to the radioprotective effects of DMSO as part of a therapeutic dose.
A study published in 2010 claimed that DNA treated with 10% DMSO, once irradiated, led to deadly effects such as chromosome aberration being suppressed. However, 10% remained toxic.
When DMSO lowered the concentration to 5%, the results showed proportionally lower radioprotective effects due to hydroxyl radicals’ suppression. However, it is still interesting to show another mechanism in which DMSO exerts a radioprotective effect by facilitating interrupted double-stranded DNA repair.
These effects are insignificant if the concentration is lowered to 1%. These results indicated that low concentrations of DMSO exerted a radioprotective effect by facilitating the repair of interrupted double-stranded DNA rather than suppressing the damage caused by radicals.
Another property of dimethyl sulfoxide should be mentioned, which is very important. In clinical use, this preparation can be used as an injection.
Wondering how? Dimethyl sulfoxide is a solvent, and it can dissolve almost anything. Preparations such as vitamin C, vitamin B in powder form are easily dissolved in DMSO. It is an interesting fact that the skin absorbs it extremely well. This mixture, some vitamins, minerals, and even medicine and DMSO, when we apply it on the skin, absorbs it and transports it directly into the bloodstream.
In this way, various preparations can be applied through the skin to people who need a higher concentration of the drug or preparation. About 90% is lost orally because stomach acid burns most of the capsule contents. So on that occasion, the organism absorbs only one-tenth of the contents.
What is also significant for DMSO is that this preparation increases the cell membrane’s permeability. In this way, we inject a compound into the body through the skin and increase the absorption in the cells themselves and achieve an effect ten times stronger than other transport methods.
DMSO literally “pushes” compounds into the body and cells to the bones themselves, which also absorb it very well.
DMSO and chemotherapy
This compound has shown exceptional therapeutic abilities in people suffering from malignancy and benign diseases.
With the above-mentioned ability to “push” the compounds dissolved in it into the body, Dimethylsulfoxide also has the ability to “open” both healthy and cancerous cells.
Dimethylsulfoxide increases cancer cells’ permeability and thus allows their oxidation, reduces acidity, and increases the influx of nutrients. In one part of cancer cells, DMSO can achieve a reversible process, which is very important in brain cancer because neurons do not regenerate or regenerate very slowly.
Dimethylsulfoxide increases the action of chemotherapy and up to 10 times! By increasing the cell membrane’s permeability, this preparation enables chemotherapy to destroy even the most resistant forms of malignancy.
It is known that cancer cells have a very thick cell membrane that contains specific proteins, which maintain the cancer cell and its anaerobic state. DMSO breaks down and reduces the protein coat’s density, and together with some enzymes like pancreatin, bromelain, K peptidase, and serrapeptase, it can completely burn it.
Due to all the unique properties of DMSO, we should be careful how we take it and what we mix it with, and we will talk about the process of consumption below.
Use of DMSO
Dimethyl sulfoxide can be used by applying it to the skin in a thin coat without rubbing it. It is successfully absorbed into the skin, so this process does not need additional stimulation.
Never use medical gloves or plastic for application because some DMSO materials dissolve and end up in our bodies. We wouldn’t like that, would we? Plastic in the body is the worst poison that can find us next to heavy metals.
Dimethylsulfoxide is not applied in its pure state. It is best to buy 99.99% pure DMSO, which we will dissolve later.
Dimethyl sulfoxide is best dissolved in a glass jar and mixed with a glass object, applied to the body, and smeared with a glass object such as a glass spoon.
DMSO is mixed with distilled water in a ratio of 70% DMSO, 30% distilled water. Mixing and dissolving are done immediately before application.
The maximum daily dose of this solution is 5 ml. DMSO should not be applied to only one site as it may create a rash. You can also apply it above the sore spot or any other part of the body around the hot spot.
If a rash occurs, stop taking DMSO for a few days.