For more than a decade, Life Extension® has published clinical studies demonstrating the effects in people with certain cancers who used coenzyme Q10. In clinical studies, not only have improvements been documented in patients, but the mechanisms by which coenzyme q10 has been identified have also been identified. Slows tumor growth.
These mechanisms include increasing the immune system, suppressing vascular endothelial growth factors, and altering inflammatory markers that facilitate cancer cells’ proliferation. Melanoma and breast cancer are two types of malignancies in which COQ10 has shown significant clinical improvement.
Coenzyme Q10 and cancer
Unfortunately, many media outlets have not covered these significant discoveries that could have saved many lives. One of them is a study on melanoma with or without a daily dose of coenzyme q10 in 400mg. The results were astonishing. The group taking coenzyme q10 had a 10 times lower risk of metastasis than those not taking it. This effect is even more pronounced for those who have advanced melanoma, in which case patients were 13 times less likely to develop a metastasis.
After that, great criticism fell on the National Cancer Institute, which did not fund further research, although studies have shown that this enzyme can help treat cancer. In this study, 18% of all patients showed side effects than 82% who did not have them. This would be a reason not to continue research by the institute.
It was sad to read a report from the National Cancer Institute that presented its views on the role that coenzyme q10 may play in cancer treatment and the adverse effects of this enzyme on patients. Given that this report comes to a federal agency that is generally biased against alternative therapy, our expectations of a negative response have miraculously failed.
The Federal Agency commented: We disagree with the National Cancer Institute report regarding side effects related to the study of coenzyme q10, resulting from the enzyme itself and the use of toxic chemo drugs and the effects of cancer. Life Extension® who used coenzyme q10 did not experience any side effects.
Questions and answers about coenzyme Q10
What is Coenzyme Q10?
Coenzyme Q10 (Co Q10) is a naturally produced compound in the body. Q or 10 in coenzyme Q10 refers to the groups of chemicals that make up the coenzyme. Other names also know coenzyme Q10:
– CoQ10.
– Q10.
– Vitamin Q10.
– Ubiquinone.
– Ubidecarenone.
A coenzyme helps enzymes do their job. An enzyme is a protein that increases the rate at which natural chemical reactions occur in cells. The body cells use coenzyme q10 to increase the energy needed for growth and keep the cell healthy. The body also uses coenzyme Q10 as an antioxidant. An antioxidant is a substance that protects cells from chemicals called free radicals.
Free radicals can damage DNA. Damaged DNA can also be linked to some types of cancer. Coenzyme Q10 can generally be found in larger body tissues. The highest concentration is found in the heart, liver, kidneys, and pancreas. It is least present in the lungs. The amount of coenzyme Q10 decreases as we age.
History of coenzyme Q10 as an ingredient in alternative cancer treatment:
Coenzyme Q10 was first identified in 1957, while its chemical structure was determined in 1958. Interest in coenzyme Q10 as a possible treatment for cancer began in 1961 when it was found that some cancer patients had lower coenzyme levels in their blood. Lower levels of coenzyme Q10 have been found in patients with melanoma, lymphoma, and cancers of the breast, lung, prostate, pancreas, colon, kidney, head, and neck. Studies suggest that coenzyme Q10 can help improve the immune system. Partly for this reason, the coenzyme is used in adjuvant cancer therapy.
What theory is behind the claim that coenzyme Q10 is useful in treating cancer?
Coenzyme Q10 may be useful in treating cancer because it strengthens the immune system. Studies also suggest that COQ10 directly prevents cancer cell growth. As an antioxidant, coenzyme Q10 can prevent cancer from developing.
How is COQ10 used?
The usual method is orally as a capsule. It can also be given by injection. In animal studies, coenzyme Q10 was used by injection.
Animal research
Clinical studies have been performed in animals with coenzyme Q10. Research has been done in the laboratory using animals to determine if they will be useful in humans. These preclinical studies were performed before human testing began. Most laboratory studies of coenzyme Q10 are based on animal body reactions.
The next preclinical study was the relationship between coenzyme Q10 and cancer. Studies of coenzyme Q10 in animals have strengthened the immune system and help the body fight certain infections. This coenzyme helped protect the heart in animals, given the anticancer drug doxorubicin, leading to heart muscle damage. Animal laboratory tests have proven that coenzyme Q10 stops cancer cells’ growth and development.
Have human clinical trials been conducted?
So far, there have been no well-designed clinical trials involving many people that would be studied to discover how Q10 coenzyme acts in cancer treatment. There have been some clinical trials with a small number of people. Basically, all studies were random. Randomized studies provide the highest level of evidence. In these studies, volunteers were randomly assigned one to two or more groups comparing different treatment-related factors in controlled studies until one group called the control group received a new treatment.
The control group is compared with the groups in which new treatments are obtained, and when comparing, the results can be compared, and conclusions can be drawn. Most scientific journals have experts who review research reports before publishing them to determine the evidence and draw conclusions. Some randomized trials of coenzyme Q10 as a cancer treatment have been published in scientific journals. The following information was published from the above studies for coenzyme Q10 based on human research:
Investigation of the positive effect of coenzyme q10 on doxyrubicinin
-A sample of 20 patients was tested on whether coenzyme q10enzyme protects the heart from damage caused by atracillin from the drug doxorubicin. This study shows that coenzyme Q10 reduces the harmful effects of doxorubicin on the heart.
Coenzyme Q10 studies in adjuvant therapy for breast cancer
Small judges are made during coenzyme Q10 after standard treatment in breast cancer patients.
A coenzyme study was performed Q10 as adjunctive therapy in 32 breast cancer patients. It was reported that the symptoms of this disease disappeared in 6 patients. The exact details were found in only 3 out of 6 patients. The researchers also indicated that all patients improved their quality of life, used fewer painkillers, and did not receive decreased body weight.
In the following study, two patients who had breast cancer and underwent surgery were given a high dose of coenzyme q10 for 4 months. In these patients, cancer completely disappeared.
Are there any side effects with coenzyme Q10?
No serious side effects have been reported with the use of coenzyme q10.
The most common side effects are as follows:
-Rash
-Nausea
-Insomnia
-Pain in the upper abdomen
-Dizziness
-Feeling tired
-Headache
Certain medications used to lower blood pressure cholesterol and lower blood sugar levels may reduce the effectiveness of COQ10. Coenzyme Q10 can change the way the body uses warfarin and insulin.
